152213-63-3

Basic information

• Product Name: 6-Bromo-1H-indole-3-acetic acid methyl ester
• Synonyms: 6-Bromo-1H-indole-3-acetic acid methyl ester;1H-INDOLE-3-ACETIC ACID, 6-BROMO-A-OXO-;methyl 2-(6-bromo-1H-indol-3-yl)acetate
• CAS NO: 152213-63-3
• Molecular Formula: C₁₁H₁₀BrNO₂
• Molecular Weight: 268.06354
• Mol File: 152213-63-3.mol

Chemical Properties

• Boiling Point: 394.1±27.0 °C(Predicted)
• Appearance: /
• Density: 1.569±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 15.73±0.30(Predicted)
• CAS DataBase Reference: 6-Bromo-1H-indole-3-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-1H-indole-3-acetic acid methyl ester(152213-63-3)
• EPA Substance Registry System: 6-Bromo-1H-indole-3-acetic acid methyl ester(152213-63-3)

Safety Data

• Hazardous Substances Data: 152213-63-3(Hazardous Substances Data)

Usage

Uses

Used in Research and Laboratory Experiments:
6-Bromo-1H-indole-3-acetic acid methyl ester is used as a research chemical for studying plant physiology and biochemistry due to its ability to stimulate root and cell elongation in plants. This makes it a valuable tool for understanding plant growth and development mechanisms.
Used in Pharmaceutical and Agrochemical Production:
6-Bromo-1H-indole-3-acetic acid methyl ester is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, contributing to the development of new compounds with potential applications in medicine and agriculture.
Used in Plant Growth Regulation:
6-Bromo-1H-indole-3-acetic acid methyl ester is used as a plant growth regulator for its potential to enhance crop productivity. It is employed in the development of new plant growth regulators and agrochemicals that can improve agricultural yields and efficiency.
Used in Crop Productivity Improvement:
In the agricultural industry, 6-Bromo-1H-indole-3-acetic acid methyl ester is used as a growth enhancer to improve crop productivity. Its application aims to increase the efficiency of plant growth, leading to higher yields and better crop quality.

Upstream product

• 152213-66-6 2-(6-bromo-1H-indol-3-yl)acetic acid 
• 67-56-1 methanol 
• 152213-61-1 2-(6-bromo-1H-indol-3-yl)acetonitrile 
• 52415-29-9 6-bromo-1H-indole 
• 59609-63-1 6-Bromogramine 
• 947605-02-9 methyl (2,6-dibromo-1H-indol-3-yl)acetate 
• 1912-33-0 Indole-3-acetic acid methyl ester 
• 10075-50-0 5-bromo-1H-indole 
• 830-93-3 N-[(5-bromo-1H-indol-3-yl)methyl]-N,N-dimethylamine 

Relevant articles and documents

Concise synthesis of deformylflustrabromine, a marine indole alkaloid, through a 2-propynyl dicobalt hexacarbonyl complex

Deformylflustrabromine, a marine indole alkaloid, was synthesized from 6-bromotryptamine, a plausible biosynthetic precursor, without protection of the amino group by a two-step reverse prenylation involving the Nicholas reaction and reductive decomplexat

New synthetic approach to paullones and characterization of their SIRT1 inhibitory activity

A series of 7,12-dihydroindolo[3,2-d][1]benzazepine-6(5H)-ones (paullones) substituted at C9/C10 (Br) and C2 (Me, CF3, CO2Me) have been synthesized by a one-pot Suzuki-Miyaura cross-coupling of an o-aminoarylboronic acid and methyl 2-iodoindoleacetate followed by intramolecular amide formation. Other approaches to the paullone scaffold based on Pd-catalyzed C-H activation were unsuccessful. In vitro enzymatic assay with recombinant human SIRT-1 indicated a strong inhibitory profile for the series, in particular the analogue with a methoxycarbonyl group at C2 and a bromine at C9. These compounds are, in general, inducers of granulocyte differentiation of the U937 acute leukemia cell line and cause a marked increase in pre-G1 of the cell cycle.

Total synthesis of (±)-chartelline C

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