15504-60-6

Basic information

• Product Name: CHEMBRDG-BB 5762406
• Synonyms: CHEMBRDG-BB 5762406;3-(1-PIPERIDINYLCARBONYL)PHENOL;UKRORGSYN-BB BBV-102961;3-(1-piperidinylcarbonyl)phenol(SALTDATA: FREE);(3-hydroxyphenyl)-1-piperidinylmethanone
• CAS NO: 15504-60-6
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.25
• Mol File: 15504-60-6.mol

Chemical Properties

• Boiling Point: 398.605°C at 760 mmHg
• Flash Point: 194.869°C
• Appearance: /
• Density: 1.187g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: CHEMBRDG-BB 5762406(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMBRDG-BB 5762406(15504-60-6)
• EPA Substance Registry System: CHEMBRDG-BB 5762406(15504-60-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 15504-60-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
CHEMBRDG-BB 5762406 is used as a potential anxiolytic agent for the treatment of anxiety disorders. Its selective action on the α5 subtype of the GABAA receptor suggests that it may provide therapeutic benefits with reduced sedative and cognitive side effects compared to traditional benzodiazepines.
Used in Neurological Disorders Research:
CHEMBRDG-BB 5762406 is used as a potential anticonvulsant agent for the treatment of epilepsy and other seizure disorders. Its demonstrated anticonvulsant properties in preclinical studies make it a promising candidate for further research and development in the field of central nervous system disorders.
Used in Drug Development:
CHEMBRDG-BB 5762406 is used as a target for the development of new treatments for anxiety and epilepsy. Its unique pharmacological profile and potential therapeutic benefits make it a valuable compound for further research and development in the pharmaceutical industry.

InChI:InChI=1/C12H15NO2/c14-11-6-4-5-10(9-11)12(15)13-7-2-1-3-8-13/h4-6,9,14H,1-3,7-8H2

Upstream product

• 110-89-4 piperidine 
• 99-06-9 3-Carboxyphenol 
• 586-38-9 3-Methoxybenzoic acid 
• 69001-09-8 (3-methoxyphenyl)(piperidin-1-yl)methanone 

Downstream Products

• 110925-92-3 2C₁₇H₂₆N₂O₃*C₂H₂O₄ 
• 93793-83-0 Gastralgin 
• 73279-04-6 3-[1-piperidinylmethyl]phenol 
• 73278-98-5 N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>amine 
• 106871-90-3 4-(aminosulfonyl)-N-<3-<3-(1-piperidinecarbonyl)phenoxy>propyl>-3-thiophenecarboxamide 
• 106871-91-4 1-<3-<3-(thieno<3,4-d>isothiazol-3-ylamino)propoxy>benzoyl>piperidine S',S'-dioxide 
• 106871-89-0 1-[[3-(3-aminopropoxy)phenyl]carbonyl]piperidine 
• 106871-88-9 1-<3-<3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propoxy>benzoyl>piperidine 

Relevant articles and documents

A preparation method for rosacea acetate hydrochloride

The present invention relates to the field of pharmaceutical preparation technology, in particular to a method for preparing rosatidine acetate hydrochloride. The present invention adopts m-hydroxybenzoic acid as a starting material, a wide range of sources, inexpensive, and it can be prepared by oxidation of m-hydroxytoluene, without involving a toxicity warning structure and nitrosamine impurities; at the same time, in this preparation process only involves a genotoxic warning structure substance, reducing the risk of medication of subsequent drugs.

Bifunctional organocatalysts for the asymmetric synthesis of axially chiral benzamides

Bifunctional organocatalysts bearing amino and urea functional groups in a chiral molecular skeleton were applied to the enantioselective synthesis of axially chiral benzamides via aromatic electrophilic bromination. The results demonstrate the versatilit

Enantioselective synthesis of atropisomeric benzamides through peptide-catalyzed bromination

We report the enantioselective synthesis of atropisomeric benzamides employing catalytic electrophilic aromatic substitution reactions involving bromination. The catalyst is a simple tetrapeptide bearing a tertiary amine that may function as a Br?nsted base. A series of tri- and dibrominations were accomplished for a range of compounds bearing differential substitution patterns. Tertiary benzamides represent appropriate substrates for the reaction since they exhibit sufficiently high barriers to racemization after ortho functionalization. Mechanism-driven experiments provided some insight into the basis for selectivity. Examination of the observed products at low conversion suggested that the initial catalytic bromination may be regioselective and stereochemistry-determining. A complex between the catalyst and substrate was observed by NMR spectroscopy, revealing a specific association. Finally, the products of these reactions may be subjected to regioselective metal-halogen exchange and trapping with I2, setting the stage for utility.