155892-27-6 Usage
Uses
Used in Peptide Synthesis:
FMOC-O-BUTYL-L-TYROSINE N-HYDROXYSUCCINIMIDE ESTER is used as a key component in the synthesis of peptides for its ability to form stable peptide bonds with other amino acids. The presence of the N-hydroxysuccinimide ester enhances the reactivity of the compound, making it an efficient coupling agent in the assembly of peptide chains.
Used in Biochemical Research:
In the field of biochemical research, FMOC-O-BUTYL-L-TYROSINE N-HYDROXYSUCCINIMIDE ESTER serves as a versatile tool for the study of peptide structures and functions. Its reactivity and the ease of removal of the FMOC protecting group make it suitable for exploring the properties of peptides under various conditions.
Used in Pharmaceutical Development:
FMOC-O-BUTYL-L-TYROSINE N-HYDROXYSUCCINIMIDE ESTER is utilized in the development of pharmaceuticals, particularly in the creation of novel drug candidates that involve peptide sequences. Its role in peptide synthesis allows for the design and synthesis of potential therapeutic agents with specific biological activities.
Used in Laboratory Settings:
Due to its high reactivity, FMOC-O-BUTYL-L-TYROSINE N-HYDROXYSUCCINIMIDE ESTER is handled with care in laboratory settings, where it is used for educational purposes and for training researchers in the techniques of peptide synthesis and related biochemical procedures.
Check Digit Verification of cas no
The CAS Registry Mumber 155892-27-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,8,9 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 155892-27:
(8*1)+(7*5)+(6*5)+(5*8)+(4*9)+(3*2)+(2*2)+(1*7)=166
166 % 10 = 6
So 155892-27-6 is a valid CAS Registry Number.
155892-27-6Relevant articles and documents
Site-Specific Incorporation of Multiple Thioamide Substitutions into a Peptide Backbone via Solid Phase Peptide Synthesis
Yang, Jinhua,Wang, Changliu,Yao, Chaochao,Chen, Chunqiu,Hu, Yafang,He, Guifeng,Zhao, Junfeng
, p. 1484 - 1494 (2020/01/02)
Among various peptide modification strategies, thioamide substitution by replacing the carbonyl oxygen atom of an amide bond with a sulfur atom constitutes an invaluable tool for chemical biology, for use in peptide drug discovery and protein structure-fu
Kilogram-Scale Synthesis of Osteogenic Growth Peptide (10-14) Using a Fragment Coupling Approach
Zhang, Teng,Chen, Zhenxing,Tian, Yan,Han, Bin,Zhang, Ning,Song, Wei,Liu, Zhulan,Zhao, Jinli,Liu, Jianli
supporting information, p. 1257 - 1262 (2015/09/28)
Kilogram-scale synthesis of a bioactive pentapeptide in solution by "3 + 2" fragment coupling strategy has been successively accomplished in the development of OGP (10-14), a minimal OGP-derived sequence that retains the full proliferative activity of the osteogenic growth peptide. The synthetic scheme, coupling conditions, and scaling-up of the process are systematically studied; the epimerization of the tripeptide fragment and pentapeptide are also evaluated.
Somatostatin receptor-binding peptides labeled with technetium-99m: Chemistry and initial biological studies
Pearson, Daniel A.,Lister-James, John,McBride, William J.,Wilson, David M.,Martel, Lawrence J.,Civitello, Edgar R.,Taylor, John E.,Moyer, Brian R.,Dean, Richard T.
, p. 1361 - 1371 (2007/10/03)
The synthesis of peptides which possess a high affinity for the somatostatin receptor and contain a chelator for the radionuclide technetium- 99m is described. The target compounds were designed such that they would form stable, oxotechnetium(V) chelate c
