16158-87-5

Basic information

• Product Name: N-CHLOROMETHYLMORPHOLINE
• Synonyms: 4-CHLOROMETHYL-MORPHOLINE;N-CHLOROMETHYLMORPHOLINE;Morpholine, 4-(chloroMethyl)-
• CAS NO: 16158-87-5
• Molecular Formula: C₅H₁₀ClNO
• Molecular Weight: 135.59
• Mol File: 16158-87-5.mol

Chemical Properties

• Boiling Point: 169.3°C at 760 mmHg
• Flash Point: 56.2°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 1.56mmHg at 25°C
• Refractive Index: 1.46
• PKA: 3.63±0.10(Predicted)
• CAS DataBase Reference: N-CHLOROMETHYLMORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-CHLOROMETHYLMORPHOLINE(16158-87-5)
• EPA Substance Registry System: N-CHLOROMETHYLMORPHOLINE(16158-87-5)

Safety Data

• Hazardous Substances Data: 16158-87-5(Hazardous Substances Data)

Usage

Uses

Used in Water Treatment:
N-Chloromethylmorpholine is used as a disinfectant and biocide for water treatment. It is effective in eliminating harmful microorganisms, ensuring the safety and quality of water supplies.
Used in Oilfield Applications:
In the oil and gas industry, N-Chloromethylmorpholine is utilized as a biocide to control microbial growth that can cause corrosion, reduce oil production, and lead to other operational issues.
Used in Industrial Processes:
N-CHLOROMETHYLMORPHOLINE is employed in various industrial processes as a disinfectant and biocide to prevent the growth of microorganisms that can affect the efficiency and quality of the processes.
Used as a Precursor in Pharmaceutical and Agrochemical Synthesis:
N-Chloromethylmorpholine is used as a precursor in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new and improved products in these fields.
However, it is crucial to handle N-Chloromethylmorpholine with care due to its corrosive nature and potential to cause irritation to the skin, eyes, and respiratory system. Proper safety measures should be taken during its use to minimize risks.

InChI:InChI=1/C5H10ClNO/c6-5-7-1-3-8-4-2-7/h1-5H2

Upstream product

• 5625-90-1 4-(morpholinomethyl)morpholine 
• 75-36-5 acetyl chloride 
• 126215-26-7 morpholinodibutylborane 
• 2351-69-1 1-(chloromethoxy)butane 

Downstream Products

• 3240-94-6 N-(2-chlorethyl)morpholine 
• 35594-63-9 4,4'-[2-chloro-2-(toluene-4-sulfonyl)-propane-1,3-diyl]-bis-morpholine 
• 29175-77-7 4-(2,3,5,6-tetramethoxy-benzyl)-morpholine 
• 63806-56-4 4-phenyl-but-3-en-2-one O-morpholin-4-ylmethyl-oxime 
• 38391-82-1 3-(4-dimethylamino-phenyl)-2-morpholin-4-ylmethyl-propenal 
• 29175-54-0 4-(2-methoxybenzyl)morpholine 
• 35824-66-9 N-morpholin-4-ylmethyl-N-o-tolyl-hydroxylamine 
• 20684-76-8 4-<(Diphenylphosphinoyl)methyl>morpholine 
• 244212-52-0 trimethylsilyl (morpholinomethyl)(2,4-diphenylbutyl)phosphinate 
• 77117-57-8 4-butyl-4-morpholinomethyl-1,2-diphenyl-pyrazolidine-3,5-dione 
• 47301-10-0 3-morpholin-4-yl-propionaldehyde (2,4-dinitro-phenyl)-hydrazone 
• 95107-87-2 <(methylthio)morpholinomethyl>diphenylphosphine oxide 

Relevant articles and documents

REACTION OF AMINOBORANES WITH α-CHLORO ETHERS

The reaction of aminoboranes and α-chloro ethers takes place with clavage of the B-N bond, leading to the formation of (chloromethyl)amines and (alkoxy)dialkylboranes.

Aminoalkylation of Enhydrazinones

Enhydrazinones, prepared from dimedone and N,N-disubstituted hydrazines, react with formaldehyde and secondary amines to C-aminoalkyl-derivatives, pyrazolinium betaines and methylenebis(enhydrazinones).With better yields the C-Mannich products result from the reaction with methyleniminium salts.The enhydrazinones give with two moles of formaldehyde and primary amines the corresponding tetrahydropyrimidines. - Keywords: Mannich Reaction, Vinylogous Hydrazides, Tetrahydropyrimidines, Pyrazolinium Betaines, Methylenebis(enhydrazinones)