20684-76-8Relevant articles and documents
8-chloro-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4-hydroxy-quinolizine-3-carboxylate and synthetic method thereof
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Paragraph 0035; 0036, (2017/08/28)
The invention provides 8-chloro-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4-hydroxy-quinolizine-3-carboxylate and a synthetic method thereof. The synthetic method comprises the following steps: a compound 6 and tert-butyldimethylsilyl chloride react in a firs
Copper-catalyzed α-amination of phosphonates and phosphine oxides: A direct approach to α-amino phosphonic acids and derivatives
McDonald, Stacey L.,Wang, Qiu
supporting information, p. 1867 - 1871 (2014/03/21)
A direct approach to important α-amino phosphonic acids and its derivatives has been developed by using copper-catalyzed electrophilic amination of α-phosphonate zincates with O-acyl hydroxylamines. This amination provides the first example of C=N bond formation which directly introduces acyclic and cyclic amines to the α-position of phosphonates in one step. The reaction is readily promoted at room temperature with as little as 0.5 mol % of catalyst, and demonstrates high efficiency on a broad substrate scope. A direct approach to important α-amino phosphonic acids and derivatives, by using copper-catalyzed electrophilic amination of α-phosphonate zincates using O-acylhydroxylamines, is described. This amination is the first example of C=N bond formation which directly introduces acyclic and cyclic amines to the α-position of phosphonates in one step. The reaction proceeds at room temperature with as little as 0.5 mol % of the catalyst. Copyright
A New Access to 3-(2'-Aminovinyl)indoles and Their First Diels-Alder Reactions
Pindur, Ulf,Otto, Christian
, p. 403 - 406 (2007/10/02)
3-Acylindoles react with α-amino-α'-diphenylphosphinoyl-substituted carboanions to 3-(2'-aminovinyl)indoles (7 and 12) via carbinols.The electron-rich 3-vinylindoles 7 and 12 undergo Diels-Alder reactions with N-phenylmaleimide.
