161891-80-1

Basic information

• Product Name: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)
• Synonyms: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)
• CAS NO: 161891-80-1
• Molecular Formula: C₈H₁₁NO₃S
• Molecular Weight: 201.24
• Product Categories: THIAZOLE
• Mol File: 161891-80-1.mol

Chemical Properties

• Boiling Point: 297.1±20.0 °C(Predicted)
• Appearance: /
• Density: 1.276±0.06 g/cm3(Predicted)
• PKA: 12.91±0.20(Predicted)
• CAS DataBase Reference: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)(161891-80-1)
• EPA Substance Registry System: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)(161891-80-1)

Safety Data

• Hazardous Substances Data: 161891-80-1(Hazardous Substances Data)

Upstream product

• 3411-58-3 L-cysteine ethylester 
• 1372541-86-0 ethyl 2-(diethoxymethyl)-2-thiazoline-4-carboxylate 
• 73956-17-9 ethyl 2-formyl-1,3-thiazole-4-carboxylate 
• 75-16-1 methylmagnesium bromide 
• 73956-16-8 ethyl 2-(diethoxymethyl)-1,3-thiazole-4-carboxylate 
• 76275-85-9 ethyl 2-<1-(benzoyloxy)ethyl>thiazole-4-carboxylate 
• 186581-53-3 diazomethane 

Downstream Products

• 13139-47-4 2-acetylthiazole-4-carboxylic acid 
• 160060-21-9 2-acetylthiazol-4-carboxylic acid ethyl ester 

Relevant articles and documents

Easy access to 2-alkyl and 2-arylthiazolines using a modified heteropolyacid catalysis: Application to the synthesis of bacillamide A

A straightforward access to 2-alkyl and 2-arylthiazolines by condensation of-aminothiols on nitriles, catalyzed by phosphotungstic acid (2%) under microwave irradiation, is described. This method has been directly applied to a short and efficient synthesi

A Convenient Synthesis of Methyl 2-thazoline-4-carboxylate, an Important Skeleton of Cyclothiazomycin

The convenient syntheses of a few methyl 2-(1-amino)alkenyl thiazoline-4-carboxylates and methyl 2-thiazoline-4-carboxylate have been accomplished.The latter is an important portial skeleton of macrobicyclic peptide antibiotic cyclothiazomycin.

Synthesis of ozonolysis products of myxothiazol

By applying the Hantzsch thiazole procedure, the synthesis of bithiazole derivatives (2 and (±)-3) corresponding to degradation products of myxothiazol was achieved. Optically active (S)-3 (87-88% ee) and its analog (S)-16 (91% ee) were obtained through enantioselective hydrolysis of the corresponding acetates ((±)-18, (±)-20 and (±)-21) using lipase in water- saturated organic solvent.