162648-32-0Relevant articles and documents
PYRAZOLOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY
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Page/Page column 84, (2015/06/25)
A series of substituted pyrazolo[1,5-a]pyridine derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
NEW PYRIDINE ANALOGUES
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Page/Page column 108, (2008/06/13)
The present invention relates to certain new pyridin analogues of Formula (I) Chemical formula should be inserted here. Please see paper copy Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
NOVEL BENZAMIDINE COMPOUND
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Page/Page column 44-45, (2008/06/13)
A novel compound, or a pharmaceutically acceptable salt thereof, represented by the formula (1) wherein the characters are as defined in the description. Thus, there can be provided an activated blood coagulation factor X inhibitor and a novel anti(blood)
Novel class of potent 4-arylalkyl substituted 3-isoxazolol GABAA antagonists: Synthesis, pharmacology, and molecular modeling
Fr?lund, Bente,J?rgensen, Anne T.,Tagmose, Lena,Stensb?l, Tine B.,Vestergaard, Henrik T.,Engblom, Christine,Kristiansen, Uffe,Sanchez, Connie,Krogsgaard-Larsen, Povl,Liljefors, Tommy
, p. 2454 - 2468 (2007/10/03)
A number of analogues of the low-efficacy partial GABAA agonist 5-(4-piperidyl)-3-isoxazolol (4-PIOL, 5), in which the 4-position of the 3-isoxazolol ring was substituted by different groups, were synthesized and tested as GABAA rece
Hindered esters of rapamycin
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, (2008/06/13)
A compound of the structure STR1 wherein R and R1 are each, independently, STR2 or hydrogen; R2 and R3 are each, independently, alkyl, arylalkyl, or R2 and R3 may be taken together to form a cycloalky