16423-68-0 Usage
Chemical Properties
red to brown powder
Uses
Different sources of media describe the Uses of 16423-68-0 differently. You can refer to the following data:
1. antibacterial
2. Erythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products.
3. Biological stain; color additive.
4. Erythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.
Preparation
fluorescent element (C.I. Acid Yellow 73, C.I. 45350) or ethanol in aqueous solution of the four iodine, then into sodium salt.
Definition
ChEBI: An organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid.
General Description
Erythrosin B (C.I. 45430)for microscopy Certistain?, is a dry dye for microscopy that is often used as a counterstain, vizualising proteins, connective tissues, fibers and keratin in sample material of human origin. Depending on user requirements and personal preferences, it can be used for the preparation of the commonly used aqueous or alcoholic Erythrosin B staining solutions. As the dye belongs to the portfolio of Certistain? dyes, it is chemically analyzed according to strict specifications before release (CE marked and IVD product) and a high staining quality, with reliable staining results is guaranteed. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
Flammability and Explosibility
Notclassified
Biochem/physiol Actions
Erythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. Erythrosin B is an artificial food dye that induces hyperkinesis when swallowed by susceptible children. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus.
Properties and Applications
blue light pink. Soluble in water is cherry red, no fluorescence. The strong sulfuric acid is palm in light yellow, diluted into palm yellow light precipitation. In water solution to join sodium hydroxide to create soluble red precipitate.
Standard
Light Fastness
Soaping
Persperation Fastness
Oxygen bleaching
Fastness to seawater
Fading
Stain
Fading
Stain
Fading
Stain
ISO
1
3
4
1
2-3
Standard
Light Fastness
Fading
Stain
ISO
1
Check Digit Verification of cas no
The CAS Registry Mumber 16423-68-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,4,2 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16423-68:
(7*1)+(6*6)+(5*4)+(4*2)+(3*3)+(2*6)+(1*8)=100
100 % 10 = 0
So 16423-68-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2
16423-68-0Relevant articles and documents
Technique for preparing erythrosin B
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Paragraph 0048; 0051; 0052; 0053; 0054, (2017/04/19)
The invention discloses a technique for preparing erythrosin B. The technique comprises the steps of 1, making fluorescein which serves as the start material react with iodate to generate erythrosine under the action of a solvent and a catalyst; 2, making the erythrosine prepared in step 1 react with alkali to generate the erythrosine B under the action of a solvent. The technique has the advantages that operation is easy, cost is low, yield is high, pollution is light, and iodine utilization rate is high. The technique is suitable for industrial production and is suitable for production of most relevant enterprises.
Single label comparative hybridization
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, (2015/01/06)
The present invention provides methods of detecting and mapping chromosomal or genetic abnormalities associated with various diseases or with predisposition to various diseases, or to detecting the phenomena of large scale copy number variants. In particular, the present invention provides advanced methods of performing array-based comparative hybridization that allow reproducibility between samples and enhanced sensitivity by using the same detectable label for both test sample and reference sample nucleic acids. Invention methods are useful for the detection or diagnosis of particular disease conditions such as cancer, and detecting predisposition to cancer based on detection of chromosomal or genetic abnormalities and gene expression level. Invention methods are also useful for the detection or diagnosis of hereditary genetic disorders or predisposition thereto, especially in prenatal samples. Moreover, invention methods are also useful for the detection or diagnosis of de novo genetic aberrations associated with post-natal developmental abnormalities.
