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Basic Information
CAS No.: 16423-68-0
Name: ERYTHROSIN B
Article Data: 2
Molecular Structure:
Molecular Structure of 16423-68-0 (ERYTHROSIN B)
Formula: C20H6I4O5.2Na
Molecular Weight: 833.883
Synonyms: Hexacert Red No. 3;Japan Red 3;Japan Red No. 3;New Pink Bluish Geigy;Synerid;Usacert FD &;Water Pink 176575;1671Red;Acid Red 51;Aizen Erythrosine;Dolkwal Erythrosine;E 127;Edicol Supra Erythrosine A;Erythrosin B sodium salt;Erythrosine;Erythrosine 36003;Erythrosine Bluish;
EINECS: 240-474-8
Density: 0.98
Melting Point: >300oC (Decomposes)
Boiling Point: 628.3 °C at 760 mmHg
Flash Point: 333.8 °C
Solubility: Soluble in water
Appearance: red to brown powder
Hazard Symbols: R22:Harmful if swallowed.;
Risk Codes: 22
Safety: 36
PSA: 81.65000
LogP: 6.96060
Synthetic route
258864-54-9

trihexyl(tetradecyl)phosphonium chloride

16423-68-0

2,4,5,7-tetraiodo-6-hydroxy-9-(2-carboxyphenyl)fluorone (erythrosine), ionic form

2C32H68P(1+)*C20H6I4O5(2-)

Conditions
ConditionsYield
In dichloromethane; water for 48h;
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Chemistry

Molecular Formula: C20H6I4Na2O5
Formula Weight: 879.86
Synonyms: Fd and c red 3 ; Erythrosin , disodium salt ; Eeythrosin bluish ; Iodoeosin sodium
Melting Point: 142~144 °
Density of Eryhrosin b (16423-68-0) : 0.98
Boiling Point: 693.2 °C at 760 mmHg
Flash Point: 285 °C
Colour Index : 45430
Solubility: Eryhrosin b (16423-68-0) is soluble in water.
Chemical Properties: Eryhrosin b (16423-68-0) is a red to brown powder. Odorless.

Toxicity Data With Reference

1.    

mrc-smc 100 mg/L

    MUREAV    Mutation Research. 138 (1984),153.
2.    

dni-hmn:leu 500 mg/L

    NEZAAQ    Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. 30 (1975),574.
3.    

cyt-ham:fbr 600 mg/L

    FCTOD7    Food and Chemical Toxicology. 22 (1984),623.
4.    

orl-rat LD50:1840 mg/kg

    SCPHA4    Scientia Pharmaceutica. 47 (1979),39.
5.    

ivn-rat LD50:200 mg/kg

    SCPHA4    Scientia Pharmaceutica. 47 (1979),39.
6.    

orl-mus LD50:1264 mg/kg

    EAPHA6    Eastern Pharmacist. 24 (1981),125.
7.    

ivn-mus LD50:370 mg/kg

    APPHAX    Acta Poloniae Pharmaceutica. 9 (1952),127.

Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. Questionable carcinogen with experimental tumorigenic data. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Na2O and I.

Safety: WARNING: Harmful through skin absorbtion or ingestion.
Hazard Codes : Xn: Harmful
Risk Statements : 22: Harmful if swallowed 
Safety Statements : 36: Wear suitable protective clothing 
WGK Germany : 3
RTECS : LM5950000

Specification

Storage: Protect against physical damage. Keep in a tightly closed container, stored in a cool, dry, ventilated area.