ERYTHROSIN B

Base Information

• Chemical Name: ERYTHROSIN B
• CAS No.: 16423-68-0
• Molecular Formula: C20H6I4O5^.2Na
• Molecular Weight: 833.883
• Hs Code.: 3204.12 Oral rat LD50: 1840 mg/kg
• Mol file: 16423-68-0.mol

Synonyms:Hexacert Red No. 3;Japan Red 3;Japan Red No. 3;New Pink Bluish Geigy;Synerid;Usacert FD &;Water Pink 176575;1671Red;Acid Red 51;Aizen Erythrosine;Dolkwal Erythrosine;E 127;Edicol Supra Erythrosine A;Erythrosin B sodium salt;Erythrosine;Erythrosine 36003;Erythrosine Bluish;

Chemical Property of ERYTHROSIN B

Chemical Property:

• Appearance/Colour: red to brown powder
• Vapor Pressure: 2.22E-16mmHg at 25°C
• Melting Point: >300oC (Decomposes)
• Boiling Point: 628.3 °C at 760 mmHg
• PKA: 4.1(at 25℃)
• Flash Point: 333.8 °C
• PSA: 81.65000
• Density: 0.98
• LogP: 6.96060
• Storage Temp.: Store at +5°C to +30°C.
• Solubility.: 100g/l
• Water Solubility.: Soluble in water
• XLogP3: 6.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 833.6394
• Heavy Atom Count: 29
• Complexity: 797

Purity/Quality:

HPLC≥95% ^*data from raw suppliers

ErythrosineBDisodiumSalt(TechnicalGrade) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R22:Harmful if swallowed.
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Dyes -> Di- and Triaryl Dyes
• Canonical SMILES: C1=CC=C(C(=C1)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)I)[O-])I)I)I)C(=O)[O-]
• Description: FD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1 .
• Uses: antibacterial Erythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products. Biological stain; color additive. Erythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.

Technology Process of ERYTHROSIN B

There total 2 articles about ERYTHROSIN B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

erythrosine B (15905-32-5,767625-50-3) → 2',4',5',7'-tetraiodofluorescein disodium salt (16423-68-0,63467-67-4)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃; for 4.5h; Autoclave; Large scale;

Reference yield:

→ 2',4',5',7'-tetraiodofluorescein disodium salt (16423-68-0,63467-67-4)

Guidance literature:

Reference yield: 94.0%

erythrosin (568-63-8,16423-68-0) + phenethylamine (64-04-0) → sodium; 2,4,5,7-tetraiodo-6-oxo-9-(2-phenethylcarbamoyl-phenyl)-6H-xanthen-3-olate

Guidance literature:

With pyridinium p-toluenesulfonate; benzotriazol-1-ol; diisopropyl-carbodiimide; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 4h;

DOI:10.1055/s-2004-834819

upstream raw materials:

erythrosine B

Downstream raw materials:

C₂₀H₆I₄O₅^(1-)*Na⁽¹⁺⁾

C₂₀H₇I₄O₅^(2-)*2Na⁽¹⁺⁾

Refernces

• 1、 -. "Single label comparative hybridization". . . Retrieved 2015/01/06.