16718-05-1

Basic information

• Product Name: 3-BENZENESULFONYLTHIOPHENE
• Synonyms: BUTTPARK 48\04-83;3-BENZENESULFONYLTHIOPHENE;3-(PHENYLSULFONYL)THIOPHENE;3-(PHENYLSULPHONYL)THIOPHENE;3-BENZENESULFONYLTHIOPHENE 98%;Phenyl-3-thienylsulfone
• CAS NO: 16718-05-1
• Molecular Formula: C₁₀H₈O₂S₂
• Molecular Weight: 224.3
• Mol File: 16718-05-1.mol

Chemical Properties

• Melting Point: 115 °C
• Boiling Point: 391.6 °C at 760 mmHg
• Flash Point: 190.6 °C
• Appearance: /
• Density: 1.34g/cm³
• Vapor Pressure: 5.5E-06mmHg at 25°C
• Refractive Index: 1.615
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-BENZENESULFONYLTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZENESULFONYLTHIOPHENE(16718-05-1)
• EPA Substance Registry System: 3-BENZENESULFONYLTHIOPHENE(16718-05-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: S24/25:Avoid contact with skin and eyes.
• WGK Germany: 3
• Hazardous Substances Data: 16718-05-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Benzene sulfonylthiophene serves as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of new drugs with specific therapeutic properties, contributing to advancements in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 3-benzenesulfonylthiophene is utilized as an essential intermediate for the production of agrochemicals. Its reactivity and properties enable the creation of effective compounds for crop protection and other agricultural applications.
Used in Dye and Pigment Production:
3-Benzene sulfonylthiophene is employed as a building block in the production of dyes and pigments. Its chemical structure contributes to the development of colorants with specific characteristics, such as color intensity, stability, and solubility, which are crucial for various industries including textiles, plastics, and inks.
Used in Liquid Crystal Industry:
3-BENZENESULFONYLTHIOPHENE also plays a role in the liquid crystal industry, where it is used as a building block for the production of liquid crystals. The unique properties of 3-benzenesulfonylthiophene contribute to the development of liquid crystal materials with specific optical, electrical, and thermal properties, which are vital for applications in displays, sensors, and other technologies.

InChI:InChI=1/C10H8O2S2/c11-14(12,10-6-7-13-8-10)9-4-2-1-3-5-9/h1-8H

Upstream product

• 51175-71-4 thiophene-3-sulfonyl chloride 
• 38111-44-3 phenylzinc(II) bromide 
• 98-09-9 benzenesulfonyl chloride 
• 872-31-1 3-Bromothiophene 
• 873-55-2 sodium benzenesulfonate 

Relevant articles and documents

Nickel-Catalyzed Synthesis of Diaryl Sulfones from Aryl Halides and Sodium Sulfinates

A novel nickel-catalyzed cross-coupling of sulfinic acid salts with aryl halides is described. The reaction provides access to various diaryl sulfones in moderate to excellent yields. A broad range of functional groups and heteroaromatic compounds is tolerated under the reaction conditions.

CuI catalyzed sulfonylation of organozinc reagents with sulfonyl halides

In this study, a facile CuI catalyzed synthesis of sulfones involving a nucleophilic addition of functionalized organozinc reagents to organic sulfonyl chlorides is realized. This reaction proceeds efficiently at room temperature, giving rise to various functional group substituted sulfones, generally in moderate to high yields. The method provides a novel, simple, and promising strategy for functionalized sulfone synthesis in the research field of sulfur chemistry. the Partner Organisations 2014.