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3-bromo-7,8-difluoroquinoline is a halogenated quinoline derivative with the molecular formula C9H4BrF2N. It is a chemical compound that contains bromine and fluorine atoms, which can alter its biochemical and pharmacological properties. 3-bromo-7,8-difluoroquinoline has potential applications in medicinal chemistry and drug discovery due to the diverse biological activities of quinoline derivatives, such as antibacterial, antimalarial, and anticancer properties.

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  • 1686108-69-9 Structure
  • Basic information

    1. Product Name: 3-bromo-7,8-difluoroquinoline
    2. Synonyms: 3-bromo-7,8-difluoroquinoline
    3. CAS NO:1686108-69-9
    4. Molecular Formula: C9H4BrF2N
    5. Molecular Weight: 244.0355664
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1686108-69-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-bromo-7,8-difluoroquinoline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-bromo-7,8-difluoroquinoline(1686108-69-9)
    11. EPA Substance Registry System: 3-bromo-7,8-difluoroquinoline(1686108-69-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1686108-69-9(Hazardous Substances Data)

1686108-69-9 Usage

Uses

Used in Medicinal Chemistry:
3-bromo-7,8-difluoroquinoline is used as a potential candidate for the development of new therapeutic agents in medicinal chemistry. The introduction of bromine and fluorine atoms into the quinoline core can enhance its biological activities and make it a promising pharmaceutical candidate.
Used in Drug Discovery:
3-bromo-7,8-difluoroquinoline is used as a potential lead compound in drug discovery. Its unique structure and properties make it a valuable tool for the development of new drugs with improved efficacy and selectivity.
Used in Anticancer Applications:
3-bromo-7,8-difluoroquinoline is used as a potential anticancer agent. Quinoline derivatives have been studied for their anticancer properties, and the introduction of bromine and fluorine atoms may further enhance its activity against cancer cells.
Used in Antibacterial Applications:
3-bromo-7,8-difluoroquinoline is used as a potential antibacterial agent. Quinoline derivatives have been known for their antibacterial properties, and the halogenated version may exhibit improved activity against bacterial infections.
Used in Antimalarial Applications:
3-bromo-7,8-difluoroquinoline is used as a potential antimalarial agent. Quinoline derivatives have been studied for their antimalarial properties, and the introduction of bromine and fluorine atoms may enhance its efficacy against malaria-causing parasites.

Check Digit Verification of cas no

The CAS Registry Mumber 1686108-69-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,8,6,1,0 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1686108-69:
(9*1)+(8*6)+(7*8)+(6*6)+(5*1)+(4*0)+(3*8)+(2*6)+(1*9)=199
199 % 10 = 9
So 1686108-69-9 is a valid CAS Registry Number.

1686108-69-9Upstream product

1686108-69-9Downstream Products

1686108-69-9Relevant articles and documents

3-amino -7,8-difluoro-quinoline and wherein the intermediate synthesis method

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Paragraph 0020; 0021; 0022; 0023, (2016/10/10)

The invention provides 3-amino-7,8-difluoroquinoline and a synthesis method of an intermediate body of the 3-amino-7,8-difluoroquinoline. 3-amino-7,8-difluoromethylquinoline is prepared by three steps of carrying out substitution reaction on 7,8-difluoroquinoline, carrying out condensation reaction on 3-bromine-7,8-difluoroquinoline and carrying out amino deprotection reaction on 7,8-difluoro-3-tertoxy carbonyl amino quinoline; 7,8-difluoroquinoline-3-formic acid is prepared by three steps of carrying out substitution reaction on 7,8-difluoroquinoline, carrying out carbonyl insertion reaction on 3-bromine-7,8-difluoroquinoline and carrying out hydrolysis reaction on 7,8-difluoroquinoline-3-methyl formate. The synthesis method of the intermediate body of 3-amino-7,8-difluoroquinoline is simple in route, high in total yield, convenient to operate, simple in post-treatment, free of poisonous reagent and suitable for large-scale production.

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