17264-78-7

Basic information

• Product Name: sodium 2-methoxybenzoate
• Synonyms: benzoic acid, 2-methoxy-, sodium salt (1:1); Sodium 2-methoxybenzoate; SODIUM METHYLSALICYLATE
• CAS NO: 17264-78-7
• Molecular Formula: C₈H₇O₃*Na
• Molecular Weight: 174.1291
• Mol File: 17264-78-7.mol

Chemical Properties

• CAS DataBase Reference: sodium 2-methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium 2-methoxybenzoate(17264-78-7)
• EPA Substance Registry System: sodium 2-methoxybenzoate(17264-78-7)

Safety Data

• Hazardous Substances Data: 17264-78-7(Hazardous Substances Data)

Upstream product

• 612-16-8 (2-methoxyphenyl)methanol 
• 579-75-9 2-Methoxybenzoic acid 
• 824-78-2 4-nitrophenol sodium salt 

Downstream Products

• 75-46-7 trifluoromethan 
• 120608-89-1 2-Methoxy-benzoic acid difluoromethyl ester 
• 55153-19-0 2-oxo-2-phenylethyl 2-methoxybenzoate 
• 54-21-7 sodium salicylate 
• 2553-04-0 ortho-methoxybenzophenone 
• 286401-34-1 bis(pentafluorophenyl)antimony(III) 2-methoxybenzoate 
• 286401-39-6 pentafluorophenylantimony(V) bis(2-methoxybenzoate) dichloride 
• 286401-36-3 tris(m-fluorophenyl)antimony(V) bis(2-methoxybenzoate) 
• 286401-37-4 tris(p-fluorophenyl)antimony(V) bis(2-methoxybenzoate) 
• 286401-35-2 tris(pentafluorophenyl)antimony(V) bis(2-methoxybenzoate) 

Relevant articles and documents

Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C-H Functionalization Cascades

Structurally complex benzo- and spiro-fused N-polyheterocycles can be accessed via intramolecular Pd(0)-catalyzed alkene 1,2-aminoarylation reactions. The method uses N-(pentafluorobenzoyloxy)carbamates as the initiating motif, and this allows aza-Heck-type alkene amino-palladation in advance of C-H palladation of the aromatic component. The chemistry is showcased in the first total synthesis of the complex alkaloid (+)-pileamartine A, which has resulted in the reassignment of its absolute stereochemistry.

Electronic and steric effects: How do they work in ionic liquids? the case of benzoic acid dissociation

(Figure Presented) The need to have a measure of the strength of some substituted benzoic acids in ionic liquid solution led us to use the protonation equilibrium of sodium p-nitrophenolate as a probe reaction, which was studied by means of spectrophotometric titration at 298 K. In order to evaluate the importance of electronic effect of the substituents present on the aromatic ring, both electron-withdrawing and -donor substituents were taken into account. Furthermore, to have a measure of the importance of the steric effect of the substituents both para- and ortho-substituted benzoic acids were analyzed. The probe reaction was studied in two ionic liquids differing for the ability of the cation to give hydrogen bond and π-π interactions, namely [bm 2im][NTf2] and [bmpyrr][NTf2]. Data collected show that benzoic acids are less dissociated in ionic liquid than in water solution. Furthermore, the equilibrium constant values seem to be significantly affected by both the nature of ionic liquid cation and the structure of the acid. In particular, the ortho-steric effect seems to operate differently in water and in the aromatic ionic liquid, determining in this solvent medium a particular behavior for ortho-substituted benzoic acids.

METAL-CATALYZED SIMULTANEOUS PRODUCTION OF HYDROGEN AND ALKALINE SALTS OF ORGANIC ACIDS

Metal catalysis of the dehydrogenation of primary alcohols to alkaline salts of the corresponding organic acids is described.Conditions (120-170 deg C) are much milder than those required by the uncatalyzed reactions (220-260 deg C).Hydrogen is evolved in the ratio of two molecules per molecule of alcohol.