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Benzaldehyde, 3-bromo-5-fluoro-2-hydroxy-, is an organic compound with the molecular formula C7H5BrFO2. It is a derivative of benzaldehyde, featuring a bromine and fluorine atom attached to the carbon ring, along with a hydroxyl group. Benzaldehyde, 3-bromo-5-fluoro-2-hydroxyis utilized in various organic synthesis processes and serves as a building block for the preparation of pharmaceuticals and fine chemicals. Its unique structure also positions it for potential applications in medicinal chemistry and drug discovery.

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  • 178546-34-4 Structure
  • Basic information

    1. Product Name: Benzaldehyde, 3-broMo-5-fluoro-2-hydroxy-
    2. Synonyms: Benzaldehyde, 3-broMo-5-fluoro-2-hydroxy-;3-bromo-5-fluoro-2-hydoxybenzaldehyde
    3. CAS NO:178546-34-4
    4. Molecular Formula: C7H4BrFO2
    5. Molecular Weight: 219.0078632
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 178546-34-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Benzaldehyde, 3-broMo-5-fluoro-2-hydroxy-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Benzaldehyde, 3-broMo-5-fluoro-2-hydroxy-(178546-34-4)
    11. EPA Substance Registry System: Benzaldehyde, 3-broMo-5-fluoro-2-hydroxy-(178546-34-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 178546-34-4(Hazardous Substances Data)

178546-34-4 Usage

Uses

Used in Organic Synthesis:
Benzaldehyde, 3-bromo-5-fluoro-2-hydroxy-, is used as a key intermediate in organic synthesis for the production of various chemical compounds. Its unique functional groups allow for versatile reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Preparation:
Benzaldehyde, 3-bromo-5-fluoro-2-hydroxyis used as a building block in the preparation of pharmaceuticals. Its presence in the molecular structure can influence the pharmacological properties of the final drug, contributing to the development of new therapeutic agents.
Used in Fine Chemicals Production:
Benzaldehyde, 3-bromo-5-fluoro-2-hydroxy-, is utilized in the production of fine chemicals, which are high-purity chemicals used in various industries, including pharmaceuticals, agriculture, and materials science.
Used in Medicinal Chemistry and Drug Discovery:
Due to its unique structure and functional groups, Benzaldehyde, 3-bromo-5-fluoro-2-hydroxy-, is used in medicinal chemistry for the design and synthesis of new drug candidates. Its potential applications in drug discovery make it a promising compound for the development of novel therapeutics.

Check Digit Verification of cas no

The CAS Registry Mumber 178546-34-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,5,4 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 178546-34:
(8*1)+(7*7)+(6*8)+(5*5)+(4*4)+(3*6)+(2*3)+(1*4)=174
174 % 10 = 4
So 178546-34-4 is a valid CAS Registry Number.

178546-34-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-bromo-5-fluoro-2-hydroxybenzaldehyde

1.2 Other means of identification

Product number -
Other names PC2607

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:178546-34-4 SDS

178546-34-4Relevant articles and documents

Imidazo ring PAR4 antagonist and medical applications thereof

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Paragraph 0383-0386, (2020/01/12)

The invention relates to an imidazo ring compound represented by formula (I) or formula (II), or a pharmaceutically acceptable salt or ester or solvate thereof. The compound disclosed by the inventioncan be used for preparing medicines for preventing or treating thromboembolic diseases.

BENZO-FUSED HETEROCYCLIC DERIVATIVES USEFUL AS AGONISTS OF GPR120

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Paragraph 0534, (2014/09/30)

The present invention is directed to benzo-fused heterocyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by GPR120. More particularly, the compounds of the present invention are agonists of GPR120, useful in the treatment of, such as for example, Type II diabetes mellitus.

2-CARBOXAMIDE-7-PIPERAZINYL-BENZOFURAN DERIVATIVES 774

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Page/Page column 32, (2011/01/05)

The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted;R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocycl

Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners

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Page/Page column 184, (2008/12/05)

The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE

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Page/Page column 21, (2008/06/13)

[From equivalent EP1710233A1] The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; R2 is lower alkyl, halo-lower alkyl, cycloalkyl, heterocycloalkyl, aryl, aralkyl, arylalkenyl, aryloxy-lower alkyl, heteroaryl, heteroaryl-lower alkyl, etc; R3, R4, R5 and R6 are each hydrogen, halogen, cyano, lower alkyl, halo-lower alkyl, lower alkoxy, hydroxy, aryl, etc; provided that at least one of R3, R4, R5 and R6 is other than hydrogen. Compound (I) of the present invention shows a potent adenosine A2A receptor antagonistic activity, and are useful for treating or preventing a disease mediated by adenosine A2A receptors such as motor function disorders, depression, anxiety disorders, cognitive function disorders, cerebral ischemia disorders, restless legs syndrome and the like.

2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS

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Page 70, (2008/06/13)

The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.

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