179115-41-4

Basic information

• Product Name: 2-[(1-BENZYL-4-PIPERIDINYL)AMINO]-3-CHLORONAPHTHOQUINONE
• Synonyms: 2-[(1-BENZYL-4-PIPERIDINYL)AMINO]-3-CHLORONAPHTHOQUINONE
• CAS NO: 179115-41-4
• Molecular Formula: C₂₂H₂₁ClN₂O₂
• Molecular Weight: 380.87
• Mol File: 179115-41-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(1-BENZYL-4-PIPERIDINYL)AMINO]-3-CHLORONAPHTHOQUINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(1-BENZYL-4-PIPERIDINYL)AMINO]-3-CHLORONAPHTHOQUINONE(179115-41-4)
• EPA Substance Registry System: 2-[(1-BENZYL-4-PIPERIDINYL)AMINO]-3-CHLORONAPHTHOQUINONE(179115-41-4)

Safety Data

• Hazardous Substances Data: 179115-41-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-[(1-Benzyl-4-piperidinyl)amino]-3-chloronaphthoquinone is used as an intermediate in the synthesis of various pharmaceuticals for its anti-cancer and antibacterial properties. It is valued for its potential to contribute to the development of new drugs targeting a range of diseases.
Used in Organic Synthesis:
In the field of organic synthesis, 2-[(1-Benzyl-4-piperidinyl)amino]-3-chloronaphthoquinone is used as a key component in the creation of diverse organic compounds, leveraging its unique structural features to form novel molecules with potential applications in various industries.
Used in Anticancer Research:
2-[(1-Benzyl-4-piperidinyl)amino]-3-chloronaphthoquinone is utilized as a subject of anticancer research, where its potential to inhibit cancer cell growth and proliferation is explored. It is studied for its ability to target specific pathways and mechanisms within cancer cells, offering a new avenue for cancer treatment.
Used in Antibacterial Applications:
2-[(1-BENZYL-4-PIPERIDINYL)AMINO]-3-CHLORONAPHTHOQUINONE is also used in antibacterial applications, where its ability to combat bacterial infections is investigated. Its potential to disrupt bacterial cell functions and inhibit their growth makes it a candidate for new antimicrobial agents.
Used in Antioxidant Studies:
2-[(1-Benzyl-4-piperidinyl)amino]-3-chloronaphthoquinone is used in antioxidant studies to understand its capacity to neutralize free radicals and protect cells from oxidative damage, which could have implications for the treatment of various diseases associated with oxidative stress.
Used in Photodynamic Therapy:
In the context of photodynamic therapy, 2-[(1-Benzyl-4-piperidinyl)amino]-3-chloronaphthoquinone is studied for its potential to be activated by light to produce a therapeutic effect, particularly in the treatment of cancer and other diseases where localized effects are desired.

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 100-44-7 benzyl chloride 
• 41661-47-6 piperidin-4-one 
• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 50541-93-0 4-amino-1-benzylpiperidine 

Relevant articles and documents

Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy

Thanks to the widespread use and safety profile of donepezil (1) in the treatment of Alzheimer's disease (AD), one of the most widely adopted multi-target-directed ligand (MTDL) design strategies is to modify its molecular structure by linking a second fragment carrying an additional AD-relevant biological property. Herein, supported by a proposed combination therapy of 1 and the quinone drug idebenone, we rationally designed novel 1-based MTDLs targeting Aβ and oxidative pathways. By exploiting a bioisosteric replacement of the indanone core of 1 with a 1,4-naphthoquinone, we ended up with a series of highly merged derivatives, in principle devoid of the “physicochemical challenge” typical of large hybrid-based MTDLs. A preliminary investigation of their multi-target profile identified 9, which showed a potent and selective butyrylcholinesterase inhibitory activity, together with antioxidant and antiaggregating properties. In addition, it displayed a promising drug-like profile.

Composition for Distructing Microalgae

The present invention relates to a composition for destroying microalgae, more specifically, to a composition for destroying microalgae containing naphthoquinone compounds having a specific exchange group. The composition for destroying microalgae, according to the present invention, can prevent green tide and red tide by being processed in areas such as cultivation facilities for microalgae, areas in which the green tide or the red tide occur, or areas expected to occur the green tide or the red tide.

Diamine derivatives of quinone and uses thereof

Diamine derivatives of quinones, and related compounds, including salts thereof, that modulate the levels of gene expression in cellular systems, such as cancer cells, are disclosed, along with methods for preparing such compounds and derivatives, as well as pharmaceutical compositions containing these compounds and derivatives as active ingredients. Methods of using these as compounds and derivatives as therapeutic agents are also described.