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Benzyl 2-methylpiperidine-1,2-dicarboxylate is a chemical compound with the molecular formula C18H21NO4. It is derived from piperidine, a heterocyclic amine, and contains a carboxylate group. Benzyl 2-methylpiperidine-1,2-dicarboxylate is a white to off-white crystalline powder, known for its potential medicinal properties and its use in organic synthesis and pharmaceutical drug production.

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  • 180609-56-7 Structure
  • Basic information

    1. Product Name: Benzyl 2-methylpiperidine-1,2-dicarboxylate
    2. Synonyms: Benzyl 2-methylpiperidine-1,2-dicarboxylate;1,2-Piperidinedicarboxylic acid 2-methyl-1-(phenylmethyl)ester;1-benzyl 2-methyl piperidine-1,2-dicarboxylate
    3. CAS NO:180609-56-7
    4. Molecular Formula: C15H19NO4
    5. Molecular Weight: 277.32
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 180609-56-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 390.4±42.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.187
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: -3.33±0.40(Predicted)
    10. CAS DataBase Reference: Benzyl 2-methylpiperidine-1,2-dicarboxylate(CAS DataBase Reference)
    11. NIST Chemistry Reference: Benzyl 2-methylpiperidine-1,2-dicarboxylate(180609-56-7)
    12. EPA Substance Registry System: Benzyl 2-methylpiperidine-1,2-dicarboxylate(180609-56-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 180609-56-7(Hazardous Substances Data)

180609-56-7 Usage

Uses

Used in Organic Synthesis:
Benzyl 2-methylpiperidine-1,2-dicarboxylate is used as a reagent in organic synthesis for its ability to facilitate various chemical reactions, contributing to the creation of a wide range of organic compounds.
Used in Pharmaceutical Production:
As a precursor in the production of pharmaceutical drugs, benzyl 2-methylpiperidine-1,2-dicarboxylate plays a crucial role in the synthesis of new medicinal compounds, potentially leading to the development of novel treatments for various health conditions.
Used in Medicinal Research:
Benzyl 2-methylpiperidine-1,2-dicarboxylate is studied for its potential medicinal properties, including its possible use as a treatment for conditions such as hypertension and neurological disorders, due to its unique chemical structure and reactivity.
Used in Research and Development:
In the pharmaceutical and chemical industries, benzyl 2-methylpiperidine-1,2-dicarboxylate is used as a research compound to explore its properties and potential applications, furthering scientific understanding and innovation in these fields.
It is important to handle benzyl 2-methylpiperidine-1,2-dicarboxylate with care due to its potentially hazardous properties, and it is typically stored under controlled conditions to ensure safety and stability.

Check Digit Verification of cas no

The CAS Registry Mumber 180609-56-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,6,0 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 180609-56:
(8*1)+(7*8)+(6*0)+(5*6)+(4*0)+(3*9)+(2*5)+(1*6)=137
137 % 10 = 7
So 180609-56-7 is a valid CAS Registry Number.

180609-56-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-O-benzyl 2-O-methyl piperidine-1,2-dicarboxylate

1.2 Other means of identification

Product number -
Other names Methyl N-Cbz-pieridine-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:180609-56-7 SDS

180609-56-7Relevant articles and documents

DERIVATIVES OF HETEROCYCLIC α-IMINOCARBOXYLIC ACIDS. 3. SYNTHESIS OF N-ALKOXYCARBONYL AND N-ALKOXYCARBONYLALKENYL DERIVATIVES OF α-IMINOCARBOXYLIC ACIDS.

Nurdinov, R.,Liepin'sh, E. E.,Kalvin'sh, I. Ya.

, p. 1347 - 1351 (1993)

By the interaction of L-proline, L-thioproline, pipecolic acid, tetrahydro-1,4-thiazine-3-carboxylic acid, and diastereomeric esters of tetrahydro-1,4-thiazine-3,5-dicarboxylic acid with methyl chloroformate, methyl propiolate, and acetylenecarboxylic aci

PROCESS FOR THE PRODUCTION OF COBIMETINIB

-

, (2019/05/22)

The present invention relates to a novel route of synthesis for the production of enantiomerically pure Cobimetinib, new intermediates in the synthesis of Cobimetinib and an amorphous Cobimetinib hemifumarate salt comprising a high salt content.

Formation of N-acyl-N,N'-dicyclohexylureas from DCC and arenecarboxylic acids in the presence of hydroxybenzotriazole in CH2CI2 at room temperature

Kaiser, Carlos R.,Pinheiro, Alessandra C.,De Souza, Marcus V. N.,Wardell, James L.,Wardell, Solange M.S.V.

experimental part, p. 468 - 472 (2009/08/15)

The syntheses of N-acyl-N',N'-dicyclohexylureas from 1,3- dicyclohexylcarbodiimide and arenecarboxylic acids [p-XC6H 4CO2H (X = H or NO2), 2-, 3- or 4-pyridinecarboxylic acid and pyrazinecarboxylic acid] in the

1H-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent PARP inhibitors

-

Page/Page column 20-21, (2008/06/13)

Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of For

DERIVATIVES OF HETEROCYCLIC α-IMINOCARBOXYLIC ACIDS. 4. REDUCTION OF N-ALKOXYCARBONYL DERIVATIVES OF α-IMINOCARBOXYLIC ACIDS.

Nurdinov, R.,Liepin'sh, E. E.,Kalvin'sh, I. Ya.

, p. 1352 - 1357 (2007/10/02)

When N-methoxycarbonyl and N-benzoxycarbonyl derivatives of methyl esters of aziridine-2-carboxylic acid, L-proline, L-thioproline, and pipecolic acid interact with NaBH4 in tert-butanol/methanol, the products of reduction of the C-methoxycarbonyl group o

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