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1-(2,4-DINITROBENZYL)-2,4-DINITROBENZENE, also known as 2,2',4,4'-Tetranitrodiphenylmethane (CAS# 1817-76-1), is a pale yellow solid with chemical properties that make it useful in various applications. It is an organic compound that can be utilized in the synthesis of other organic compounds.

1817-76-1

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1817-76-1 Usage

Uses

Used in Organic Synthesis:
1-(2,4-DINITROBENZYL)-2,4-DINITROBENZENE is used as a synthetic intermediate for the production of various organic compounds. Its chemical properties allow it to be a valuable building block in the synthesis of complex organic molecules, which can be used in different industries such as pharmaceuticals, agrochemicals, and materials science.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(2,4-DINITROBENZYL)-2,4-DINITROBENZENE is used as a key intermediate in the synthesis of drug molecules. Its unique structure and reactivity make it suitable for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
1-(2,4-DINITROBENZYL)-2,4-DINITROBENZENE is also used in the agrochemical industry as a precursor for the synthesis of various agrochemicals, such as pesticides and herbicides. Its properties enable the development of effective and environmentally friendly solutions for crop protection.
Used in Materials Science:
In the field of materials science, 1-(2,4-DINITROBENZYL)-2,4-DINITROBENZENE can be used as a component in the development of new materials with specific properties. Its chemical structure can contribute to the creation of materials with improved performance in various applications, such as coatings, adhesives, and polymers.

Check Digit Verification of cas no

The CAS Registry Mumber 1817-76-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,1 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1817-76:
(6*1)+(5*8)+(4*1)+(3*7)+(2*7)+(1*6)=91
91 % 10 = 1
So 1817-76-1 is a valid CAS Registry Number.

1817-76-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2,4-dinitrophenyl)methyl]-2,4-dinitrobenzene

1.2 Other means of identification

Product number -
Other names 1,1'-methylenebis(2,4-dinitro-benzene)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1817-76-1 SDS

1817-76-1Relevant articles and documents

Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents

Martins, Cristina,Gunaratnam, Mekala,Stuart, John,Makwana, Vaidahi,Greciano, Olga,Reszka, Anthony P.,Kelland, Lloyd R.,Neidle, Stephen

, p. 2293 - 2298 (2007)

The design, synthesis, biophysical and biochemical evaluation is presented of a new series of benzylamino-substituted acridines as G-quadruplex binding telomerase inhibitors. Replacement of the previously reported anilino substituents by benzylamino group

Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity

Nunhart, Patrik,Konko?ová, Eva,Janovec, Ladislav,Jend?elovsky, Rastislav,Vargová, Jana,?evc, Juraj,Matejová, Mária,Miltáková, Beata,Fedoro?ko, Peter,Kozurkova, Mária

, (2020)

A series of new 3,6,9-trisubstituted acridine derivatives with fluorine substituents on phenyl ring were synthesized and their interaction with calf thymus DNA was investigated. Analysis using UV–Vis absorbance spectra provided valuable information about

Antiprotozoal activity and DNA binding of dicationic acridones

Montalvo-Quirós, Sandra,Taladriz-Sender, Andrea,Kaiser, Marcel,Dardonville, Christophe

supporting information, p. 1940 - 1949 (2015/04/21)

Dicationic acridone derivatives were synthesized and their antiparasitic activity was evaluated. Acridones displayed in vitro nanomolar IC50 values against Trypanosoma brucei rhodesiense STIB900 with selectivity indices >1000. Compounds 1b, 3a,

CANCER TREATMENT USING SPECIFIC 3,6,9-SUBSTITUTED ACRIDINES

-

Figure 1, (2008/06/13)

The present invention relates to a 3,6,9 acridine compound and optionally substituted derivatives thereof that may be useful in the treatment of cancer. The invention also provides compositions comprising the compounds and uses thereof.

Therapeutic acridone and acridine compounds

-

Page/Page column 36; sheet 1, (2008/06/13)

The present invention pertains to acridone and acridine compounds of formula (I), wherein either: (a) K is ═O, L is —H, alpha is a single bond, beta is a double bond, gamma is a single bond (acridones); or, (b) K is a 9-substituent, L is absent, alpha is

The proton transfer reaction between bis(2,4-dinitrophenyl)methane and nitrogen bases in dimethyl sulfoxide and toluene solvents

Jarczewski, Arnold,Schroeder, Grzegorz,Leffek, Kenneth T.

, p. 468 - 473 (2007/10/02)

Rate constants have been measured for the proton and deuteron transfer reactions of bis(2,4-dinitrophenyl)methane (1) with 1,1,3,3-tetramethylguanidine (TMG) and 1,5-diazabicycloundec-7-ene (DBU) in dimethyl sulfoxide (DMSO) and toluene solvents.Eq

Transient nitronic acid formation in the protonation of the carbanion of 2,2',4,4'-tetranitrodiphenylmethane in acidic methanol

Terrier, Francois,Lelievre, Jacques,Chatrousse, Alain-Pierre,Schaal, Robert,Farrell, Patrick, G.

, p. 1980 - 1986 (2007/10/02)

Rates of deprotonation of 2.2',4,4'-tetranitrodiphenylmethane (1) by a variety of bases B- and of protonation of the resulting carbanion (2) by the conjugated acids BH in methanol have been measured at 20 deg C.The Broensted αBH coefficients for protonation of 2 by phenol and carboxylic acid buffers are equal to 0.58 and 0.43 respectively, as compared with αBH values of 0.59 and 0.52 respectively, for the same reactions in 50percent H2O-50percent DMSO.On the other hand, a comparison of the intrinsic rate constants kBH0 (in the Marcus sense) in the two solvents reveals that the effect of going from 50percent H2O - 50percent DMSO to methanol is is to lower kArOH0 for the phenol reactions by a factor 2 but to increase kRCOOH0 for carboxylic acid reactions by a factor of 5.It is shown that the solvent effects on αBH and kBH0 can all be understood in the context of the Principle of Imperfect Synchronisation (PIS) recently proposed by Bernasconi.In addition, a fast equilibrium protonation of the carbanion 2 is found to precede its conversion to 1 at low pH, i.e., pHa value associated with the ionization of 2,H is ca 4.25

Solvent Dependence of the Ionization of Nitrophenylmethanes

Fogel, Paula,Farrel, Patrick G.,Lelievre, Jacques,Chatrousse, Alain P.,Terrier, Francois

, p. 711 - 716 (2007/10/02)

The solvent dependence of proton abstraction from various nitrophenylmethanes has been examined for aqueous dimethyl sulphoxide and methanolic dimethyl sulphoxide solutions.Even though the compounds studied vary considerably in thermodynamic acidity (pKa), their proton-abstraction rates all show the same solvent dependence.It is suggested that the transition states for these reactions all occur at similar positions on the reaction pathway, and that transition state imbalances exist for these proton transfers.

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