71535-97-2Relevant articles and documents
Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity
Nunhart, Patrik,Konko?ová, Eva,Janovec, Ladislav,Jend?elovsky, Rastislav,Vargová, Jana,?evc, Juraj,Matejová, Mária,Miltáková, Beata,Fedoro?ko, Peter,Kozurkova, Mária
, (2019/11/13)
A series of new 3,6,9-trisubstituted acridine derivatives with fluorine substituents on phenyl ring were synthesized and their interaction with calf thymus DNA was investigated. Analysis using UV–Vis absorbance spectra provided valuable information about
Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents
Martins, Cristina,Gunaratnam, Mekala,Stuart, John,Makwana, Vaidahi,Greciano, Olga,Reszka, Anthony P.,Kelland, Lloyd R.,Neidle, Stephen
, p. 2293 - 2298 (2008/02/02)
The design, synthesis, biophysical and biochemical evaluation is presented of a new series of benzylamino-substituted acridines as G-quadruplex binding telomerase inhibitors. Replacement of the previously reported anilino substituents by benzylamino group
Therapeutic acridone and acridine compounds
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Page/Page column 36; sheet 1, (2008/06/13)
The present invention pertains to acridone and acridine compounds of formula (I), wherein either: (a) K is ═O, L is —H, alpha is a single bond, beta is a double bond, gamma is a single bond (acridones); or, (b) K is a 9-substituent, L is absent, alpha is