18753-56-5

Basic information

• Product Name: 5-Benzyl-3-phenylisoxazole
• Synonyms: 5-Benzyl-3-phenylisoxazole
• CAS NO: 18753-56-5
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 0
• Mol File: 18753-56-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Benzyl-3-phenylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzyl-3-phenylisoxazole(18753-56-5)
• EPA Substance Registry System: 5-Benzyl-3-phenylisoxazole(18753-56-5)

Safety Data

• Hazardous Substances Data: 18753-56-5(Hazardous Substances Data)

Upstream product

• 3442-15-7 1,4-diphenylbutane-1,3-dione 
• 873-67-6 benzonitrile oxide 
• 2327-99-3 1-phenylpropadiene 
• 10147-11-2 propargyl benzene 
• 10341-75-0 (E)-1-phenylethanone oxime 
• 95092-10-7 N-methoxy-N-methyl-2-phenylacetamide 
• 103-82-2 phenylacetic acid 
• 101-97-3 Ethyl 2-phenylethanoate 
• 98-86-2 acetophenone 
• 698-16-8 benzohydroximoyl chloride 
• 52201-28-2 1-(1-methyl-2-phenyl ethenyl)-pyrrolidine 
• 103-79-7 1-phenyl-acetone 
• 886-66-8 1,4-diphenyl-1,3-butadiyne 
• 536-74-3 phenylacetylene 

Downstream Products

• 1373038-58-4 C₁₆H₁₄N₂O₃S 
• 1373038-62-0 C₁₆H₁₂ClNO₃S 

Relevant articles and documents

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Methods of making heteroaromatic compounds comprising a 5- membered ring, and dihydro forms thereof, by a metal catalysed 5-endo-cyclisation of alkynes (acetylenes) are disclosed. The methods involve the use of a catalyst comprising a silver salt, more preferably a silver (I) salt, which is employed as a heterogeneous catalyst for the cyclisation reaction. The methods can produce different types of heteroaromatic compounds and are capable of producing highly substituted products, i.e. products in which the 5-membered ring is disubstituted, trisubstituted or, with further simple reactions, tetrasubstituted. The methods described herein generally the advantages that they use conditions and reagents that are benign, cheap and flexible and amenable to scale up, and in which the only by-product is water.