190957-76-7

Basic information

• Product Name: Furo[3,2-c]pyridine-4-carbonitrile(9CI)
• Synonyms: Furo[3,2-c]pyridine-4-carbonitrile(9CI);Furo[3,2-c]pyridine-4-carbonitrile;Furo[3,2-C]Pyridine-4-Carbonitrile(WX683518)
• CAS NO: 190957-76-7
• Molecular Formula: C₈H₄N₂O
• Molecular Weight: 144.13
• Product Categories: PYRIDINE
• Mol File: 190957-76-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Furo[3,2-c]pyridine-4-carbonitrile(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Furo[3,2-c]pyridine-4-carbonitrile(9CI)(190957-76-7)
• EPA Substance Registry System: Furo[3,2-c]pyridine-4-carbonitrile(9CI)(190957-76-7)

Safety Data

• Hazardous Substances Data: 190957-76-7(Hazardous Substances Data)

Upstream product

• 557-21-1 zinc(II) cyanide 
• 31270-80-1 4-chlorofuro[3,2-c]pyridine 
• 271-92-1 furo[3,2-c]pyridine 
• 57420-06-1 furo<3,2-c>pyridine N-oxide 
• 151-50-8 potassium cyanide 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 190957-88-1 Furo[3,2-c]pyridine-4-carboxylic acid ethyl ester 
• 190957-79-0 Furo[3,2-c]pyridine-4-carboxamide 
• 193750-71-9 4-acetylfuro[3,2-c]pyridine 
• 190957-82-5 Furo[3,2-c]pyridine-4-carboxylic acid 

Relevant articles and documents

Late-stage Pd-catalyzed Cyanations of Aryl/Heteroaryl Halides in Aqueous Micellar Media

New technology is described that enables late stage ppm Pd-catalyzed cyanations of highly complex molecules, as well as a wide variety of aryl and heteroaryl halides possessing sensitive functional groups. These reactions are efficient in water containing nanomicelles, formed from a commercially available and inexpensive surfactant. The implications for advancing drug synthesis and discovery are apparent.

Pyrimidone compound and application thereof

The invention discloses a pyrimidone compound, pharmaceutically acceptable salt and solvate thereof, and provides a method for preparing the compounds, a composition containing the compounds and medicinal application of the compounds in preparation of medicines for treating diseases or disorders related to EED protein and/or PRC2 protein complex action mechanisms.

5-Aminofuro[3,2-c]pyridinium tosylates and substituted furo[3,2-c]pyridine n-oxides: Synthesis and reactions

5-Aminofuro[3,2-c]pyridinium tosylates 2a-2c were synthesized by direct N-amination of furo[3,2-c]pyridines 1a-1c with O-(4-methylbenzenesulfonyl)hydroxylamine in dichloromethane. Zwitterionic furo[3,2-c]pyridinium N-imides 3a-3c generated from 2a-2c and

Furopyridines. XXI [1]. Synthesis of Cyano Derivatives of Furo-[2,3-b]-,-[2,3-c]- And -[3,2-c]pyridine and Their Conversion to Derivatives Having Another Carbon-substituent

Cyanation of furo[2,3-b]-, -[2,3-c]- and -[3,2-c]pyridine N-oxides 1a, 1b and 1c by the Reissert-Henze method, reaction with benzoyl chloride and trimethylsilyl cyanide in dichloromethane and the reaction with trimethylsilyl cyanide and triethylamine in acetonitrile afforded 6-cyanofuro[2,3-b]- 2a, 7-cyanofuro[2,3-c]- 2b and 4-cyanofuro[3,2-c]pyridine 2c in moderate to excellent yield. The cyano group in 2a, 2b and 2c was converted to carboxamides 3a, 3b and 3c, ethyl imidates 5a, 5b and 5c and ethyl carboxylates 6a, 6b and 6c. Reaction of the N-oxides with trimethylsily bromide in acetonitrile gave the deoxygenated furopyridine 7a and 7d, bifuropyridyl 8b and 8c, and the N-oxide 9 of 8c.