191725-82-3

Basic information

• Product Name: Ethanone, 1-(4-methoxy-3-pyridinyl)- (9CI)
• Synonyms: Ethanone, 1-(4-methoxy-3-pyridinyl)- (9CI);3-Acetyl-4-Methoxy pyridine;1-(4-Methoxypyridin-3-yl)ethanone;1-(4-Methoxy-3-pyridinyl)ethanone;1-(4-Methoxy-3-pyridyl)ethanone;1-(4-methoxypyridin-3-yl)ethan-1-one;Ethanone, 1-(4-methoxy-3-pyridinyl)-
• CAS NO: 191725-82-3
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.16256
• Product Categories: ACETYLGROUP
• Mol File: 191725-82-3.mol

Chemical Properties

• Boiling Point: 264.2±20.0 °C(Predicted)
• Appearance: /
• Density: 1.093±0.06 g/cm3(Predicted)
• PKA: 4.75±0.18(Predicted)
• CAS DataBase Reference: Ethanone, 1-(4-methoxy-3-pyridinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-methoxy-3-pyridinyl)- (9CI)(191725-82-3)
• EPA Substance Registry System: Ethanone, 1-(4-methoxy-3-pyridinyl)- (9CI)(191725-82-3)

Safety Data

• Hazardous Substances Data: 191725-82-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-(4-methoxy-3-pyridinyl)(9CI) is used as a building block for the synthesis of various medications for the treatment of diseases such as cancer, infections, and neurological disorders. Its unique chemical structure allows it to be incorporated into the development of new drugs with potential therapeutic benefits.
Used as a Reagent in Organic Synthesis:
In addition to its pharmaceutical applications, Ethanone, 1-(4-methoxy-3-pyridinyl)(9CI) is also used as a reagent and intermediate in organic synthesis. Its versatile chemical properties make it a valuable component in the synthesis of various organic compounds, contributing to the advancement of chemical research and development.

Upstream product

• 1807467-70-4 1-(4-chloropyridin-3-yl)ethanone hydrochloride 
• 124-41-4 sodium methylate 
• 116922-69-1 rac-4-chloro-3-(1-hydroxyethyl)pyridine 
• 116922-73-7 1-(4-chloropyridin-3-yl)ethanone 

Relevant articles and documents

FUNCTIONALIZED HETROARYL ENONES EXHIBITING NRF2 ACTIVATION AND THEIR METHOD OF USE

Pharmaceutical compositions are disclosed, which include functionalized hetroaryl enones and are useful for treating or preventing a disease, disorder or condition associated with an NRF2-regulated pathway and/or which involves oxidative stress.

Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy

Nrf2 activators represent a good drug target for designing agents to treat diseases associated with oxidative stress. Building upon previous work, we designed and prepared a series of heterocyclic chalcone-based Nrf2 activators with reduced lipophilicity

Piperidine and tetrahydropyridine derivatives

A class of substituted piperidine and tetrahydropyridine derivatives, linked through the 4-position thereof via an alkylene chain to a fused bicyclic heteroaromatic moiety such as indolyl, and further substituted at the 1-position by an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl-alkyl, aryl-alkyl or heteroaryl-alkyl moiety, are selective agonists of 5-HT1 -like receptors, being potent agonists of the human 5-HT1Dα; receptor subtype whilst processing at least a 10-fold selective affinity for the 5-HT1Dα; receptor subtype relative to the 5-HT1Dβ; subtype; they are therefore useful in the treatment and/or prevention of clinical conditions, in particular migraine and associated disorders, for which a subtype-selective agonist of 5-HT1D receptors is indicated, whilst eliciting fewer side-effects, notably adverse cardiovascular events, than those associated with non-subtype-selective 5-HT1D receptor agonists.