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2-Hydroxy-1-[4-(methylsulphonyl)phenyl]ethan-1-one, also known as sulindac sulfone, is a chemical compound with potential anti-inflammatory and anti-cancer properties. It belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and is derived from the prodrug sulindac, which is known for its anti-inflammatory effects. Sulindac sulfone has been studied for its ability to inhibit the growth of cancer cells and reduce inflammation in various conditions, including arthritis and inflammatory bowel disease. It is believed to exert its effects by inhibiting the activity of enzymes involved in inflammation and cell growth, making it a promising candidate for the treatment of various inflammatory and cancer-related conditions.

197240-27-0

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197240-27-0 Usage

Uses

Used in Pharmaceutical Industry:
2-Hydroxy-1-[4-(methylsulphonyl)phenyl]ethan-1-one is used as an anti-inflammatory and anti-cancer agent for its ability to inhibit the growth of cancer cells and reduce inflammation in various conditions, such as arthritis and inflammatory bowel disease.
Used in Cancer Treatment:
2-Hydroxy-1-[4-(methylsulphonyl)phenyl]ethan-1-one is used as a potential therapeutic agent for the treatment of various types of cancer due to its ability to inhibit the growth of cancer cells.
Used in Inflammatory Conditions Treatment:
2-Hydroxy-1-[4-(methylsulphonyl)phenyl]ethan-1-one is used as a treatment for various inflammatory conditions, such as arthritis and inflammatory bowel disease, due to its ability to reduce inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 197240-27-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,2,4 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 197240-27:
(8*1)+(7*9)+(6*7)+(5*2)+(4*4)+(3*0)+(2*2)+(1*7)=150
150 % 10 = 0
So 197240-27-0 is a valid CAS Registry Number.

197240-27-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-1-(4-methylsulfonylphenyl)ethanone

1.2 Other means of identification

Product number -
Other names 2-hydroxy-1-(4-methanesulfonylphenyl)ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:197240-27-0 SDS

197240-27-0Relevant articles and documents

Spiro[indene-1,4′-oxa-zolidinones] Synthesis via Rh(III)-Catalyzed Coupling of 4-Phenyl-1,3-oxazol-2(3 H)-ones with Alkynes: A Redox-Neutral Approach

Liu, Zhongsu,Zhang, Wenjing,Guo, Shan,Zhu, Jin

, p. 11945 - 11957 (2019/10/02)

Transition-metal-catalyzed C-H activation synthesis of heterocyclic spiro[4,4]nonanes has persistently witnessed the use of additional stoichiometric transition-metal oxidant when employing C=C bond as the spiro ring closure site. Herein, we have addressed the issue by reporting a redox-neutral strategy for spiro[indene-1,4′-oxa-zolidinones] synthesis via Rh(III)-catalyzed coupling of 4-phenyl-1,3-oxazol-2(3H)-ones with alkynes. The synthesis features a broad substrate scope and high regiospecificity.

OPTICAL IMAGING CONTRAST AGENTS FOR IMAGING LUNG CANCER

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Page/Page column 20, (2008/06/13)

The invention provides contrast agents for optical imaging of lung cancer in patients. The contrast agents may be used in diagnosis of lung cancer, for follow up of progress in disease development, for follow up of treatment of lung cancer and for surgica

OPTICAL IMAGING CONTRAST AGENTS FOR IMAGING LUNG CANCER

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Page/Page column 24, (2008/06/13)

The invention provides contrast agents for optical imaging of prostate cancer in patients. The contrast agents may be used in diagnosis of prostate cancer, for follow up of progress in disease development, for follow up of treatment of prostate cancer and

Synthesis and biological evaluation of 3,4-diaryloxazolones: A new class of orally active cyclooxygenase-2 inhibitors

Puig, Carles,Miralpeix, Montserrat,Puig, Jaume,Beleta, Jordi,Huerta, Josep M.,López, Manel,Segarra, Victor,Ryder, Hamish,Palacios, José M.,Crespo, María I.,Godessart, Núria,Feixas, Joan,Ibarzo, Javier,Jiménez, Juan-Miguel,Soca, Lídia,Cardelús, Ignasi,Heredia, Ascensión

, p. 214 - 223 (2007/10/03)

A series of 3,4-diaryloxazolones were prepared and evaluated for their ability to inhibit cyclooxygenase-2 (COX-2). Extensive structure-activity relationship work was carried out within this series, and a number of potent and selective COX-2 inhibitors we

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