19788-36-4

Basic information

• Product Name: (3,5-DIMETHYL-4-ISOXAZOLYL)METHANOL
• Synonyms: BUTTPARK 97\06-59;(3,5-DIMETHYL-4-ISOXAZOLYL)METHANOL;AKOS PAO-1564;RARECHEM AL BD 0516;(3,5-Dimethylisoxazol-4-yl)methanol;3,5-Dimethylisoxazole-4-methanol;3,5-Dimethyl-4-hydroxymethylisoxazole;3,5-Dimethyl-4-isoxazolemethanol
• CAS NO: 19788-36-4
• Molecular Formula: C₆H₉NO₂
• Molecular Weight: 127.14
• Mol File: 19788-36-4.mol

Chemical Properties

• Melting Point: 76 °C
• Boiling Point: 96-97
• Flash Point: 112.1 °C
• Appearance: /
• Density: 1.137 g/cm³
• Vapor Pressure: 0.00577mmHg at 25°C
• Refractive Index: 1.497
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 13.65±0.10(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: (3,5-DIMETHYL-4-ISOXAZOLYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-DIMETHYL-4-ISOXAZOLYL)METHANOL(19788-36-4)
• EPA Substance Registry System: (3,5-DIMETHYL-4-ISOXAZOLYL)METHANOL(19788-36-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 19788-36-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
(3,5-Dimethyl-4-isoxazolyl)methanol is used as a reagent in the pharmaceutical industry for the synthesis of various drugs. Its unique structure and properties make it a valuable component in the development of new medicinal compounds.
Used in Agrochemical Production:
In the agrochemical sector, (3,5-Dimethyl-4-isoxazolyl)methanol is utilized as a building block for the creation of pesticides and other agricultural chemicals. Its role in this industry is crucial for enhancing crop protection and yield.
Used in Fragrance and Flavor Industry:
(3,5-Dimethyl-4-isoxazolyl)methanol is employed as a key ingredient in the production of fragrances and flavors, contributing to the development of novel scents and tastes for consumer products.
Used in Antifungal and Antibacterial Applications:
Due to its inherent antifungal and antibacterial properties, (3,5-Dimethyl-4-isoxazolyl)methanol is used in medical and agricultural applications to combat infections and protect crops from diseases.
Used in Synthesis of Isoxazolyl-Containing Compounds:
(3,5-Dimethyl-4-isoxazolyl)methanol is used as an intermediate in the synthesis of isoxazolyl-containing compounds, which have diverse applications across various industries, including the development of new materials and medicinal agents.

InChI:InChI=1/C6H9NO2/c1-4-6(3-8)5(2)9-7-4/h8H,3H2,1-2H3

Upstream product

• 19788-37-5 4-chloromethyl-3,5-dimethylisoxazole 
• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 50-00-0 formaldehyd 
• 2510-36-3 3,5-dimethyl-4-isoxazolecarboxylic acid 
• 17147-42-1 ethyl 3,5-dimethylisoxazole-4-carboxylate 
• 54593-26-9 3,5-dimethyl-1,2-oxazole-4-carbaldehyde 
• 56328-87-1 methyl 3,5-dimethylisoxazole-4-carboxylate 

Downstream Products

• 2510-36-3 3,5-dimethyl-4-isoxazolecarboxylic acid 
• 19788-37-5 4-chloromethyl-3,5-dimethylisoxazole 
• 54593-26-9 3,5-dimethyl-1,2-oxazole-4-carbaldehyde 
• 87967-96-2 NSC 375973 
• 146796-45-4 (3,5-dimethylisoxazol-4-yl)methanethiol 
• 146796-52-3 2-(2,4-difluorophenyl)-3-((3,5-dimethylisoxazol-4-yl)methylyhio)-1-(1,2,4-triazol-1-yl)-2-propanol 
• 146796-49-8 2-(2,4-dichlorophenyl)-3-((3,5-dimethylisoxazol-4-yl)methylyhio)-1-(1,2,4-triazol-1-yl)-2-propanol 
• 53257-32-2 4-(bromomethyl)-3,5-dimethylisoxazole 
• 1280608-67-4 C₃₉H₅₀N₂O₁₁Si 
• 1421838-38-1 methyl 2-(4-(2-(3,5-dimethylisoxazol-4-yl)-2-hydroxyethoxy)phenyl)acetate 
• 1421838-41-6 2-(4-(2-(3,5-dimethylisoxazol-4-yl)-2-oxoethoxy)phenyl)-N-((2,4-dimethylphenyl)(phenyl)methyl)acetamide 
• 1421837-32-2 C₃₀H₃₂N₂O₄ 
• 1421838-42-7 methyl 2-(1-(3,5-dimethylisoxazol-4-yl)-2-(4-(2-(((2,4-dimethylphenyl)(phenyl)methyl)amino)-2-oxoethyl)phenoxy)ethoxy)-2-methylpropanoate 

Relevant articles and documents

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Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer

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COMPOUNDS AND METHODS

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METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS

The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.

BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF

Compounds of the general formula (I): or salts thereof, which exhibit CCR5 antagonism and exert preventive and therapeutic effects against HIV infections: wherein R1 is a 5- to 6-membered aromatic ring which bears a substituent represented by the general formula: R-Z1-X-Z2- (wherein R1 is hydrogen or optionally substituted hydrocarbyl; X is optionally substituted alkylene; and Z1 and Z2 are each a heteroatom) and may be further substituted, with R being optionally bonded to the aromatic ring to form another ring; Y is optionally substituted imino; and R2 and R3 are each optionally substituted aliphatic hydrocarbyl or an optionally substituted hetero-alicyclic group.

Di-heterocyclic compounds and their use as antiviral agents

Compounds of the formulas: STR1 wherein Het is an oxazole or oxazine moiety; X is O, S or SO, n is an integer from 3 to 9, Y is an aliphatic bridge; and the various R groups represent hydrogen or various substituents as described herein, are useful as antiviral agents, especially against picornaviruses. N-(Chloroalkyl)amide intermediates for the compounds of Formula I are also active as antiviral agents. Related compounds outside the scope of the above formulas are also disclosed.

NEUTRAL DICHROMATE OXIDATION. PREPARATION AND UTILITY OF ISOXAZOLE ALDEHYDES

Isoxazole alcohols 1 can be oxidized by potassium dichromate in neutral organic media to give the corresponding aldehydes, 2 without destruction of the isoxazole ring.Isoxazole aldehydes 2 are of utility as starting materials for 4-(4'-isoxazyl)-1,4-dihydropyridines 3.