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2-(Benzyloxy)-4-fluorobenzaldehyde is an organic compound characterized by the presence of a benzyloxy group attached to the 2-position and a fluorine atom at the 4-position of a benzene ring. It features an aldehyde functional group, which makes it a versatile intermediate in organic synthesis.

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  • 202857-89-4 Structure
  • Basic information

    1. Product Name: 2-(benzyloxy)-4-fluorobenzaldehyde
    2. Synonyms: 2-(benzyloxy)-4-fluorobenzaldehyde;4-fluoro-2-(phenylmethoxy)Benzaldehyde
    3. CAS NO:202857-89-4
    4. Molecular Formula: C14H11FO2
    5. Molecular Weight: 230.2343432
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 202857-89-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(benzyloxy)-4-fluorobenzaldehyde(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(benzyloxy)-4-fluorobenzaldehyde(202857-89-4)
    11. EPA Substance Registry System: 2-(benzyloxy)-4-fluorobenzaldehyde(202857-89-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 202857-89-4(Hazardous Substances Data)

202857-89-4 Usage

Uses

Used in Pharmaceutical Industry:
2-(Benzyloxy)-4-fluorobenzaldehyde is used as a reactant for the synthesis of fluorinated hallucinogenic tryptamine derivatives. These compounds are of interest in the development of new psychoactive substances and potential therapeutic agents for various neurological and psychiatric disorders.
Used in Organic Synthesis:
Due to its unique structure and functional groups, 2-(Benzyloxy)-4-fluorobenzaldehyde can be employed as a building block in the synthesis of a wide range of organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its reactivity and selectivity in various chemical reactions make it a valuable component in the development of new synthetic routes and methodologies.

Check Digit Verification of cas no

The CAS Registry Mumber 202857-89-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,2,8,5 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 202857-89:
(8*2)+(7*0)+(6*2)+(5*8)+(4*5)+(3*7)+(2*8)+(1*9)=134
134 % 10 = 4
So 202857-89-4 is a valid CAS Registry Number.

202857-89-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-fluoro-2-phenylmethoxybenzaldehyde

1.2 Other means of identification

Product number -
Other names 2-benzyloxy-4-fiuoro-benzaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:202857-89-4 SDS

202857-89-4Relevant articles and documents

Atorvastatin Derived HMG-CoA Reductase Degradation Inducing Compound

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Paragraph 0420-0424, (2020/12/01)

The present invention relates to a HMG-CoA reductase degradation-inducing compound and, more specifically, to a bifunctional compound in which atorvastatin and E3 ubiquitin ligase binding moiety are chemically linked as HMG-CoA reductase binding moiety, to a production method thereof, to a HMG-CoA reductase degradation method using the same, and to a pharmaceutical composition for preventing or treating HMG-CoA reductase-related diseases, comprising the same.

1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS

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Page/Page column 100, (2018/04/27)

A compound of formula (I), wherein R, R1, R2, R3, Y, Y1, a, X, and Z are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne Muscular Dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

HIV INTEGRASE INHIBITORS

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, (2015/09/22)

The present invention features compounds that are HIV integrase inhibitors and therefore are useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.

COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE

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Paragraph 0058, (2016/01/25)

Provided herein are compounds of Formula (I), or a stereoisomer, a geometric isomer, an enantiomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, which are used in the treatment of HCV

N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS

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Page/Page column 64-65, (2010/11/04)

Disclosed herein are substantially pure forms of the compounds of Formula (I), (II), (III), (IV) and (V), or a pharmaceutically acceptable salt, prodrug, hydrate, solvate, polymorph, stereoisomer or ester thereof. Also disclosed are methods of inhibiting an activity of a serotonin receptor, methods inhibiting an activation of a serotonin receptor, and methods of alleviating or treating various disease conditions and side effects.

INDOLE AND BENZOFURAN 2-CARBOXAMIDE DERIVATIVES

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Page/Page column 42-43, (2008/12/05)

Compounds of Formula (I) or Formula (II) or pharmaceutically acceptable salts thereof, wherein m, n, p, Ar R1 R2, R4 R5 and R6 are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using these compounds in the treatment of Alzheimer's disease or as cognitive enhancer.

HIV INTEGRASE INHIBITORS

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Page/Page column 43, (2010/11/26)

The present invention features compounds that are HIV integrase inhibitors useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.

PHENYLAZETIDINONE DERIVATIVES

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Page/Page column 293, (2008/06/13)

Various azetidinone derivatives are described, as are pharmaceutical compositions containing these compounds and methods of treatment of diseases using these compounds. Other embodiments are also described.

SUBSTITUTED ACIDS FOR THE TREATMENT OF RESPIRATORY DISEASES

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Page/Page column 38, (2010/02/15)

The invention relates to substituted acids of formula (I), where T,W,X,Y,Z, R1 and R2 as defined in the claims, as useful pharmaceutical compounds for treating asthma and rhinitis, pharmaceutical compositions containing them, and a processes for their preparation.

Imidazole compounds and their use as adenosine deaminase inhibitors

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, (2008/06/13)

Imidazole compounds having adenosine deaminase inhibitory activity represented by the formula (I) wherein R1 is aryloxy, or aryl which is optionally substituted with suitable substituent(s); R2 is lower alkyl; R3 is hydrox

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