203065-99-0

Basic information

• Product Name: 2-Amino-2-[4-(trifluoromethyl)phenyl]acetamide
• Synonyms: 2-Amino-2-[4-(trifluoromethyl)phenyl]acetamide
• CAS NO: 203065-99-0
• Molecular Formula: C₉H₉F₃N₂O
• Molecular Weight: 218
• Mol File: 203065-99-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Amino-2-[4-(trifluoromethyl)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-2-[4-(trifluoromethyl)phenyl]acetamide(203065-99-0)
• EPA Substance Registry System: 2-Amino-2-[4-(trifluoromethyl)phenyl]acetamide(203065-99-0)

Safety Data

• Hazardous Substances Data: 203065-99-0(Hazardous Substances Data)

Usage

Functional Groups

Amide (-NH2), Trifluoromethyl (-CF3), Phenyl Ring (-C6H5)

Common Usage

Chemical and pharmaceutical research

Pharmacological Properties

Central Nervous System Stimulant: Potential stimulant effect on the CNS
Analgesic: Potential pain-relieving properties
Enzyme and Receptor Inhibition: Potential inhibitory effects on certain enzymes and receptors

Potential Applications

Development of new drugs and medications
Novel therapeutics in medicinal chemistry and drug discovery

Upstream product

• 144789-73-1 2-amino-2-[4-(trifluoromethyl)phenyl]acetic acid 
• 390815-48-2 methyl 2-amino-2-[4-(trifluoromethyl)phenyl]acetate hydrochloride 

Downstream Products

• 1108685-98-8 L-2-(2-methoxy-acetylamino)-2-(4-trifluoromethylphenyl)-acetamide 
• 950651-38-4 {2-oxo-3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.4]non-3-en-1-yl}acetic acid 
• 950651-37-3 ethyl {2-oxo-3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.4]non-3-en-1-yl}acetate 
• 950651-07-7 3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.5]dec-3-en-2-one 

Relevant articles and documents

EGFR DIMER DISRUPTORS AND USE OF THE SAME

Provided herein are compounds that modulate EGFR and methods of using the same, for example to treat cancer.

GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS

Compounds of formula (I) or a salt thereof are provided wherein R1, R2, R6, R7, R8, R9 and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture

COMPOUNDS WHICH INHIBIT THE GLYCINE TRANSPORTER AND USES THEREOF

Compounds of formula (I) and salts and solvates thereof are provided: wherein R1 to R8 and n are defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.

1-(2-ARYL-2-OXOETHYL)-3-PHENYL-1, 4-DIAZASPIRO [4.5]DEC-3-EN-2-ONE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORTER INHIBITORS

Novel acetophenone compounds of formula (I), compositions containing (I), processes for the preparation of (I), and use of (I) as inhibitors of the glycine transporter, are provided. Definitions of Ar, R5, R6, R7, R8