20488-54-4

Basic information

• Product Name: 1 2-DIFLUOROSTILBENE
• Synonyms: 1,2-DIPHENYL-TRANS-1,2-DIFLUOROETHYLENE;1 2-DIFLUOROSTILBENE;TRANS-ALPHA,BETA-DIFLUOROSTILBENE;-Difluorostilbene;trans-alpha,ßtrans-alpha,?Difluorostilbene;TRANS-ALPHA,SS-DIFLUOROSTILBENE;(E)-a,a'-Difluorostilbene
• CAS NO: 20488-54-4
• Molecular Formula: C₁₄H₁₀F₂
• Molecular Weight: 216.23
• Mol File: 20488-54-4.mol

Chemical Properties

• Boiling Point: 287.7°Cat760mmHg
• Flash Point: 106.2°C
• Appearance: /
• Density: 1.136g/cm³
• CAS DataBase Reference: 1 2-DIFLUOROSTILBENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1 2-DIFLUOROSTILBENE(20488-54-4)
• EPA Substance Registry System: 1 2-DIFLUOROSTILBENE(20488-54-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 20488-54-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1, 2-Difluorostilbene is used as a key building block in organic synthesis for the production of various functional materials. Its unique structure allows for the creation of a range of chemical compounds with specific properties, making it a valuable component in the synthesis process.
Used in Material Science:
In the field of material science, 1, 2-difluorostilbene is utilized for its potential to contribute to the development of new materials with enhanced properties. Its incorporation into material compositions can lead to improved characteristics such as stability, reactivity, or fluorescence, depending on the application.
Used in Pharmaceutical Industry:
1, 2-Difluorostilbene is used as a pharmaceutical intermediate for the development of new drugs. Its unique chemical properties make it a promising candidate for the creation of therapeutic agents that can target specific biological pathways or mechanisms.
Used in Biological Research:
As a fluorescent probe, 1, 2-difluorostilbene is employed in biological research to study cellular processes and interactions. Its fluorescence properties allow researchers to track and visualize biological events, contributing to a better understanding of various biological phenomena.
Overall, 1, 2-difluorostilbene's diverse applications across different industries underscore its importance as a versatile chemical compound with significant potential in scientific and industrial advancements.

Upstream product

• 395-00-6 (E/Z)-1-chloro-1,2-difluoro-2-phenylethene 
• 591-51-5 phenyllithium 
• 116-14-3 polytetrafluoroethylene 
• 591-50-4 iodobenzene 
• 447-14-3 1,2,2-trifluorostyrene 
• 1623-05-8 perfluoro(propyl vinyl ether) 
• 293302-61-1 (E)-(1,2-difluoro-1,2-ethenediyl) bis[tributylstannane] 
• 100-34-5 benzene diazonium chloride 
• 87282-19-7 3-fluoro-3-phenyldiazirine 
• 100-66-3 methoxybenzene 
• 100-58-3 phenylmagnesium bromide 
• 111848-25-0 {bis(dicyclohexylphosphino)ethane}(diphenylacetylene)platinum⁽⁰⁾ 
• 7732-18-5 water 
• 62-53-3 aniline 

Downstream Products

• 437-02-5 (2-fluoroethene-1,1,2-triyl)tribenzene 
• 365-01-5 2,2-difluoro-2-phenylacetophenone 
• 134-81-6 benzil 
• 384-67-8 2-chloro-2,2-difluoroacetophenone 
• 61025-19-2 C₂₃H₁₉F 
• 61025-20-5 C₂₃H₁₉F 
• 145693-39-6 epoxide of trans-α,β-difluorostyrene 
• 20488-55-5 cis-α,α'-difluorostilbene 
• 425-32-1 1,1,2,2-tetrafluoro-1,2-diphenylethane 

Relevant articles and documents

Stereoselective Preparation of (E)-(1,2-Difluoro-1,2-ethenediyl) Bis[tributylstannane] and Stereospecific Synthesis of (E)-1,2-Difluorostilbenes

(matrix presented) The novel bisstannane (E)-(1,2-difluoro-1,2-ethenediyl) bis[tributylstannane] 2 was stereoselectively prepared in a high overall yield through a sequential synthetic route from chlorotrifluoroethylene 1. The synthetic application of this novel bisstannane 2 was exemplified in the Pd(PPh3)4/Cul-catalyzed cross-coupling reactions with aryl iodides, yielding (E)-1,2-diflourostilbenes 3 in moderate to high yields.

The Versatile Behavior of Platinum Alkyne Complexes towards XeF2: Formation of Fluorovinyl and Fluorido Complexes

Reactions of platinum(0) tolane complexes, bearing a chelating ligand with P and N donor atoms, with the electrophilic fluorinating agent XeF2 give facile access to platinum(II) β-fluorovinyl fluorido complexes. A series of new platinum(II) β-fluorovinyl complexes have been synthesized and were structurally characterized. Further oxidation with XeF2 led to ortho-metalated platinum(IV) fluorido compounds. Additional reactions of platinum(0) tolane complexes, bearing a chelating P,P donor ligand, with XeF2 led to a variety of fluorido and fluorovinyl complexes.

PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS

An object of the present invention is to provide a method that enables the easy and efficient (high yield, high selectivity, low cost) preparation of a fluorine-containing olefin substituted with an organic group or groups from a fluorine-containing olefin. [Solution] The method for preparing a fluorine-containing olefin substituted with an organic group or groups, the method comprising a step of reacting a fluorine-containing olefin with an organic boron compound in the presence of an organic transition metal catalyst containing at least one transition metal selected from the group consisting of nickel, palladium, platinum, rhodium, ruthenium, and cobalt.

METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN

This invention relates to a method of reacting fluoroolefin with an organic magnesium compound in the presence of a catalyst comprising nickel or palladium so as to efficiently produce fluoroolefin, such as TFE, in which a fluorine (F) atom or atoms bonded to the sp2 hybridized carbon atom are substituted with an organic group.

Innermolecular reactions of fluorophenylcarbene inside a hemicarcerand

Photolysis of fluorophenyldiazirine, incarcerated in hemicarcerand 2, affords fluorophenylcarbene, which attacks an aryl unit of the host, leading (after rearrangement) to a fluoromethoxy/phenyltropone derivative of the hemicarcerand. The incarcerated car

REACTION OF α,β,β-TRIFLUOROSTYRENE WITH ARENEDIAZONIUM CHLORIDES. SYNTHESIS OF α,β-DIFLUOROSTILBENES

The reaction of α,β,β-trifluorostyrene with arenediazonium chlorides in the presence of copper(II) chloride as catalyst gave high yields of chloroarylation products 1-aryl-2-phenyl-1,2,2-trifluoro-3-chloroethanes.The regiospecificity of the reaction was c

ARYLPOLYFLUOROOLEFIN OXIDES.III. TRANS-α,β-DIFLUOROSTILBENE OXIDE AND ITS REACTIONS

1,2-Diphenyl-1,2-difluoro-1,2-epoxyethane was obtained by the oxidation of trans α,β-difluorostilbene with oxygen in the presence of chlorine or by the action of perbenzoic acid.The reaction of 1,2-diphenyl-1,2-difluoro-1,2-epoxyethane with cesium fluoride and also its thermolysis lead to α,α-difluorobenzyl phenyl ketone.In reaction with methanol α,β-difluorostilbene oxide forms a diphenyl-α,β-diketone, while sulfur tetrafluoride fluorinates it to 1,2-diphenyltetrafluoroethane.

ADDITION-ELIMINATION REACTIONS BETWEEN PHENYLLITHIUM AND SOME PERFLUOROVINYLETHER COMPOUNDS

Reactions between C6H5Li and C3H7OCF=CF2 (I) yield phenyl substituted perfluorovinylethers.Stoichiometry and reaction temperature dictate the degree of substitution.With each replacement of F- by C6H5- the subsequent substitutions require more forcing conditions.The F- is substituted easier than the C3F7O- during the addition-elimination reactions.