20964-94-7Relevant articles and documents
Nano-SiO2 catalyzed synthesis of β-enaminones under solvent free conditions
Alinezhad, Heshmatollah,Tajbakhsh, Mahmood,Sarkati, Malihe Norouzi,Zare, Mahboobe
, p. 1591 - 1596 (2016/08/16)
Nano-SiO2 efficiently catalyzed the synthesis of β-enaminones using direct condensation of various (cyclic and acyclic) β-diketones with aromatic and aliphatic amines under solvent-free conditions. This eco-friendly catalyst can be recovered and reused without significant loss of activity. This methodology provides a simple synthetic route to enaminones in excellent yields at room temperature. Graphical abstract: [Figure not available: see fulltext.]
Visible Light Initiated Hantzsch Synthesis of 2,5-Diaryl-Substituted Pyrroles at Ambient Conditions
Lei, Tao,Liu, Wen-Qiang,Li, Jian,Huang, Mao-Yong,Yang, Bing,Meng, Qing-Yuan,Chen, Bin,Tung, Chen-Ho,Wu, Li-Zhu
supporting information, p. 2479 - 2482 (2016/06/09)
Irradiation of a mixture of enamines and α-bromo ketones, with a catalytic amount of Ir(ppy)3 by visible light (Λ= 450 nm), enables the production of various 2,5-diaryl-substituted pyrroles in good to excellent yields. The key intermediates in
New synthesis of β -anilinochalcones by regioselective oxidation of β -anilinodihydrochalcones using iodine-DMSO
Nawghare, Beena R.,Lokhande, Pradeep D.
supporting information, p. 3287 - 3295 (2015/10/12)
β-Anilinodihydrochalcones readily undergo oxidation α to the carbonyl group region in the presence of a catalytic amount of iodine in dimethyl sulfoxide at 130 °C in good yield. Oxidation of allyloxy-substituted β-anilinodihydrochalcones to β-anilinochalcones is a preferred reaction over deallylation.
Four-component synthesis of β-enaminone and pyrazole through phosphine-free palladium-catalyzed cascade carbonylation
Shi, Lijun,Xue, Liqin,Lang, Rui,Xia, Chungu,Li, Fuwei
, p. 2560 - 2566 (2015/04/14)
The carbonylative domino synthesis of enaminones and pyrazoles has been performed with the N?N bidentate palladium catalyst to achieve excellent selectivity. These results have confirmed that the carbonylative Sonogashira coupling of iodobenzenes with ter
Anilines as substrates in consecutive four-component synthesis of novel 1-aryl-5-benzoyl-6-phenyl-3,4-dihydropyridin-2(1 H)-ones
Nordmann, Jan,Müller, Thomas J. J.
supporting information, p. 522 - 530 (2014/03/21)
The consecutive four-component synthesis of 5-acylpyridin-2(1H)-ones initiated by a copper-free alkynylation in a one-pot fashion has been expanded to include considerably less nucleophilic anilines as the amine component in the Michael addition step by altering the solvent system to 1,4-dioxane; 17 examples for the synthesis of 1-aryl-5-benzoyl-6-phenyl-3,4-dihydropyridin-2(1H) -ones were obtained in moderate to good yields.
Cross-dehydrogenative coupling between enamino esters and ketones: Synthesis of tetrasubstituted pyrroles
Zhao, Miao,Wang, Fen,Li, Xingwei
supporting information; experimental part, p. 1412 - 1415 (2012/05/04)
Tetrasubstituted pyrroles have been synthesized via the cross-dehydrogenative coupling between enamino esters and acetone. Silver carbonate proved to be an effective oxidant, and no transition metal catalyst is necessary.
A green solventless protocol for the synthesis of β-Enaminones and β -Enamino esters using silica sulfuric acid as a highly efficient, heterogeneous and reusable catalyst
Hasaninejad, Alireza,Zare, Abdolkarim,Mohammadizadeh, Mohammad Reza,Shekouhy, Mohsen,Moosavi-Zare, Ahmad Reza
experimental part, p. 1546 - 1554 (2011/12/05)
Silica sulfuric acid is utilized as a green, highly efficient, heterogeneous and recyclable catalyst for the preparation of β-enaminones and β -enamino esters from amines and β -dicarbonyl compounds under solvent-free conditions at 80 °C. Using this method, the title compounds are produced in high to excellent yields and in short reaction times.
Silica-supported LiHSO4 as a highly efficient, heterogeneous and reusable catalytic system for the solvent-free synthesis of β-enaminones and β-enamino esters
Hasaninejad,Zare,Mohammadizadeh,Shekouhy
experimental part, p. 69 - 76 (2010/10/21)
A highly efficient, simple and green procedure for the synthesis of β-enaminones and β-enamino esters is described. The reaction of aromatic and aliphatic amines with β-dicarbonyl compounds using catalytic amount of silica-supported LiHSO4 (LiHSO4/SiO2) under solvent-free conditions at 80 °C affords the title compounds in high to excellent yields and in short reaction times.
L-Proline-catalyzed synthesis of highly functionalized multisubstituted 1,4-dihydropyridines
Jiang, Huanfeng,Mai, Ronghuan,Cao, Hua,Zhu, Qiuhua,Liu, Xiaohang
supporting information; scheme or table, p. 4943 - 4953 (2010/02/16)
Highly functionalized multisubstituted 1,4-dihydropyridines 5 have been concisely synthesized in moderate to good yields vial-proline-catalyzed one-pot multicomponent reactions (MCRs) of alkynoates or alkynones 1, amines 2, β-dicarbonyl compounds 3 and aldehydes 4 under mild conditions. The MCR process involves hydroamination/Knoevenagel condensation/Michael-type addition/intramolecular cyclization processes and leads to the formation of 1,4-dihydropyridines 5. The molecular structure of 5ckaa was confirmed by single-crystal X-ray diffraction. This method is energy saving and environmentally friendly, providing easy access to diverse multisubstituted polyfunctional 1,4-dihydropyridines. The Royal Society of Chemistry 2009.
