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8-Amino-1-tetralone, a bicyclic organic compound with the molecular formula C11H13NO, features a tetralone ring structure with a carbonyl group and an amino group attached. This pale yellow solid, characterized by a slightly aromatic odor, is known for its unique chemical properties that make it a versatile compound in various industries.

210346-49-9

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210346-49-9 Usage

Uses

Used in Pharmaceutical Industry:
8-Amino-1-tetralone is used as a key intermediate in the synthesis of various pharmaceuticals for its cytotoxic properties against cancer cells. It plays a crucial role in the development of anticancer drugs, offering potential therapeutic benefits in cancer treatment.
Used in Chemical Industry:
In the chemical industry, 8-Amino-1-tetralone is utilized in the production of dyes and pigments. Its ability to form complex colorants makes it a valuable component in creating a wide range of color products for different applications.
Overall, 8-Amino-1-tetralone's diverse applications in pharmaceuticals, dyes, and pigments highlight its significance in both industrial and medicinal fields, driven by its unique chemical characteristics.

Check Digit Verification of cas no

The CAS Registry Mumber 210346-49-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,0,3,4 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 210346-49:
(8*2)+(7*1)+(6*0)+(5*3)+(4*4)+(3*6)+(2*4)+(1*9)=89
89 % 10 = 9
So 210346-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO/c11-8-5-1-3-7-4-2-6-9(12)10(7)8/h1,3,5H,2,4,6,11H2

210346-49-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-amino-3,4-dihydro-2H-naphthalen-1-one

1.2 Other means of identification

Product number -
Other names 8-AMINOTETRALONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:210346-49-9 SDS

210346-49-9Relevant articles and documents

INHINITORS OF GLI1 AS THERAPEUTIC AGENTS

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Paragraph 0155; 0157, (2020/06/10)

This disclosure relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to glioma- associated oncogene (Gli) expression. More particularly, this disclosure relate

5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE

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Page/Page column 99, (2017/02/28)

Provided in some embodiments are compounds of Formula A, as defined herein, that modulate the activity of 5-HT2C receptor. Also provided in some embodiments are methods, such as, for weight management, inducing satiety, and decreasing food intake, and for

NAPTHOQUINONES, PRO-DRUGS, AND METHODS OF USE THEREOF

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Paragraph 00159, (2017/07/06)

Provided herein are naphthoquinones compounds such as those with a hydrogen bond donating group of the formula (I): wherein: R1, R2, R3, R4, R5, and n are as defined herein. Also provided herein are pharmaceutical composition of the present compounds and methods of treatment using the compounds including their use in the treatment of cancer.

CARBAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES

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Paragraph 203-205, (2017/09/15)

The present invention relates to a pharmaceutical composition for treating or preventing CNS disorders containing a carbamate derivative compound and/or pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or prevention CNS disorders comprising administering a carbamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of CNS disorders.

Development of a new family of chiral auxiliaries

Gelat, Fabien,Richard, Vincent,Berger, Olivier,Montchamp, Jean-Luc

supporting information, p. 1819 - 1821 (2015/04/27)

A new family of chiral auxiliaries designed on a conformationally restricted version of (-)-8-phenylmenthol has been developed. Both enantiomers are available from an inexpensive synthesis conducted on multigram scale. A first application has showed compa

Photoassisted synthesis of enantiopure alkaloid mimics possessing unprecedented polyheterocyclic cores

Kumar, N.N. Bhuvan,Mukhina, Olga A.,Kutateladze, Andrei G.

supporting information, p. 9608 - 9611 (2013/07/26)

Enantiopure alkaloid mimics are synthesized via high yielding intramolecular cycloadditions of photogenerated azaxylylenes tethered to pyrroles, with further growth of molecular complexity via post-photochemical transformations of primary photoproducts. This expeditious access to structurally unprecedented polyheterocyclic cores is being developed in the context of diversity-oriented synthesis, as the modular design allows for rapid "pre-assembly" of diverse photoprecursors from simple building blocks/diversity inputs.

Rapid photoassisted access to N,O,S-polyheterocycles with benzoazocine and hydroquinoline cores: Intramolecular cycloadditions of photogenerated azaxylylenes

Mukhina, Olga A.,Bhuvan Kumar,Arisco, Teresa M.,Valiulin, Roman A.,Metzel, Greg A.,Kutateladze, Andrei G.

supporting information; experimental part, p. 9423 - 9428 (2011/11/06)

Ring the changes: A new photoassisted approach to give conformationally constrained N,O,S-polyheterocyclic scaffolds of unprecedented topologies was achieved by intramolecular [4+4] and [4+2] cycloadditions of photogenerated o-azaxylylenes (23 examples; see scheme). The precursors can be readily assembled by simple and high-yielding reactions, thus making this a powerful synthetic method amenable to high-throughput diversity-oriented synthesis.

Substituted Nitrogen Heterocycles and Synthesis and Uses Thereof

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Page/Page column 30-31, (2009/10/06)

The invention relates to a nitrogen heterocycle compound of formula 1: Also disclosed are a method of synthesizing the compound and use of the compound for treating various diseases and conditions.

Synthesis and structure-activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands

Caldwell, John P.,Matasi, Julius J.,Zhang, Hongtao,Fawzi, Ahmad,Tulshian, Deen B.

, p. 2281 - 2284 (2007/10/03)

A series of N-substituted analogs based upon the spiropiperidine core of 1 was synthesized and exhibited high binding affinity to the nociceptin (NOP) receptor. The selectivities against other known opioid receptors were determined.

N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES

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Page/Page column 41, (2008/06/13)

Novel N-phenyl-1,1,1-trifluoromethanesulfonamide compounds useful for controlling endo and/or ectoparasites in the environment are provided, together with methods of making the same, and methods of using the inventive compounds to treat parasite infestations in vivo and ex vivo.

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