21900-37-8

Basic information

• Product Name: 2,6-dimethylbenzoyl chloride
• Synonyms: Benzoyl chloride, 2,6-dimethyl- (6CI,7CI,8CI,9CI);2,6-DIMETHYLBENZOYL CHLORIDE 95%;2,6-Dimethylbenzoic acid chloride
• CAS NO: 21900-37-8
• Molecular Formula: C₉H₉ClO
• Molecular Weight: 168.62
• EINECS: 244-646-3
• Product Categories: ACIDHALIDE
• Mol File: 21900-37-8.mol

Chemical Properties

• Boiling Point: 229.5°Cat760mmHg
• Flash Point: 96.2°C
• Appearance: /
• Density: 1.136g/cm³
• Vapor Pressure: 0.0693mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2,6-dimethylbenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethylbenzoyl chloride(21900-37-8)
• EPA Substance Registry System: 2,6-dimethylbenzoyl chloride(21900-37-8)

Safety Data

• Hazardous Substances Data: 21900-37-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,6-dimethylbenzoyl chloride is used as an intermediate for the synthesis of various pharmaceuticals. It plays a crucial role in the production of drugs due to its ability to act as an acylating agent in the Friedel-Crafts acylation reaction, which is a widely used method for the synthesis of aromatic compounds.
Used in Agrochemical Industry:
In the agrochemical industry, 2,6-dimethylbenzoyl chloride is used as a key intermediate in the production of various agrochemicals. Its reactivity and stability make it a valuable component in the synthesis of pesticides and other agrochemical products.
Used in Dye and Pigment Industry:
2,6-dimethylbenzoyl chloride is used as a building block in the production of dyes, pigments, and perfumes. Its high reactivity allows for the synthesis of a wide range of organic compounds, contributing to the creation of various colorants and fragrances.
Used in Organic Synthesis:
As a versatile reagent, 2,6-dimethylbenzoyl chloride is used in organic synthesis for the preparation of a wide range of organic compounds. Its ability to act as an acylating agent makes it a valuable component in various chemical reactions, facilitating the synthesis of complex organic molecules.

InChI:InChI=1/C9H9ClO/c1-6-4-3-5-7(2)8(6)9(10)11/h3-5H,1-2H3

Upstream product

• 632-46-2 2,6-dimethylbenzoic acid 
• 87-62-7 2,6-dimethylaniline 
• 6575-13-9 2,6-dimethylbenzonitrile 

Downstream Products

• 70657-67-9 (2,6-dimethylphenyl)-N,N-dimethylcarboxamide 
• 93161-81-0 2,6-dimethyl-benzoic acid-(3-diethylamino-propylamide) 
• 14252-17-6 2,2',6-trimethylbenzophenone 
• 854671-62-8 2,6-dimethyl-benzoic acid p-tolyl ester 
• 35031-56-2 1-(2,6-dimethylphenyl)-1-propanone 
• 1225-22-5 bis(2,6-dimethylphenyl)glyoxal 
• 105515-29-5 2,6,2',6'-Tetramethyl-benzoin 
• 55321-98-7 2,6-dimethylbenzamide 
• 1123-56-4 2,6-dimethylbenzaldehyde 
• 94251-17-9 2,6-dimethyl-N-(2-morpholin-4-yl-ethyl)-benzamide 
• 94373-55-4 2,6-dimethyl-N-(3-morpholin-4-yl-propyl)-benzamide 
• 72239-25-9 N-(4,5-dihydro-thiazol-2-yl)-2,6-dimethyl-benzamide 
• 32228-72-1 Ethyl-2,6-dimethylbenzohydroxamat 
• 56263-48-0 isopropyl 2,6-dimethylbenzoate 

Relevant articles and documents

N-Ammonium Ylide Mediators for Electrochemical C-H Oxidation

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The reaction of magnesium amides with tert-butyl 2,6-dimethyl perbenzoate in tetrahydrofuran at 0 °C provides a method for the synthesis O-tert-butyl-N,N-disubstituted hydroxylamines by direct N-O bond formation with a broad functional group tolerance. Less sterically hindered magnesium amides require ortho,ortho-disubstitution on the perester electrophile component, whereas sterically encumbered magnesium amides perform comparably with either tert-butyl perbenzoate or tert-butyl 2,6-dimethyl perbenzoate. A reaction mechanism is presented to account for the observed reactivity.

DIVERSITY-ORIENTED SYNTHESIS OF N,N,O-TRISUBSTITUTED HYDROXYLAMINES FROM ALCOHOLS AND AMINES BY N-O BOND FORMATION

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