1225-22-5

Upstream product

• 21900-37-8 2,6-dimethylbenzoyl chloride 
• 18637-83-7 1,1'-oxalyldiimidazole 
• 21450-64-6 (2,6-dimethylphenyl)magnesium bromide 
• 79-37-8 oxalyl dichloride 
• 60-29-7 diethyl ether 
• 920-39-8 isopropylmagnesium bromide 
• 110-86-1 pyridine 
• 105515-29-5 2,6,2',6'-Tetramethyl-benzoin 
• 7732-18-5 water 
• 7758-99-8 copper(II) sulfate 
• 632-46-2 2,6-dimethylbenzoic acid 
• 71-43-2 benzene 
• 201230-82-2 carbon monoxide 
• 63509-96-6 2,6-xylyllithium 

Downstream Products

• 105515-29-5 2,6,2',6'-Tetramethyl-benzoin 
• 82679-08-1 α.α'-diacetoxy-2.6.2'.6'-tetramethyl-cis-stilbene 
• 82679-08-1 1,2-diacetoxy-1,2-bis(2,6-dimethylphenyl)ethene 
• 873413-90-2 2,6,2',6'-tetramethyl-3,3'-dinitro-benzil 
• 860511-67-7 3,3'-diamino-2,6,2',6'-tetramethyl-benzil 

Relevant academic research and scientific papers

Synthesis of Symmetrical Diaryl 1,2-Diketones from Grignard Reagents and 1,1'-Oxalylimidazole

Symmetrical diaryl 1,2-diketones (α-diketones) are obtained in reasonably good yields when readily accessible 1,1'-oxalylimidazole is treated with two equivalents of an aryl Grignard reagent.

A Direct Access to α-Diones from Oxalyl Chloride

Cross-coupling reactions of oxalyl chloride with organocopper reagents, derived from Grignard reagents, cuprous bromide, and lithium bromide, provide a simple and straightforward method for the synthesis of symmetrical α-diones in very good yields.

Synthesis of highly hindered 1,2-diaryl diketones and of cis- and trans-1,2-diacetoxy-1,2-bis(aryl)ethenes

Highly hindered 1,2-diaryl diketones can be synthesized in good yields by the reaction of 1-aryllithium with CO in THF solution at atmospheric pressure; preparation of cis- and trans-1,2-diacetoxy-1,2-bis(Mes)ethene can be also afforded by a similar procedure and further quenching with Ac2O.