2260-12-0

Basic information

• Product Name: 2-AMINO-3-PHENYL-BUTYRIC ACID
• Synonyms: 2-AMINO-3-PHENYL-BUTYRIC ACID;2-AMINO-3-PHENYLBUTANOIC ACID;2-azanyl-3-phenyl-butanoic acid
• CAS NO: 2260-12-0
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• Mol File: 2260-12-0.mol

Chemical Properties

• Boiling Point: 306 °C at 760 mmHg
• Flash Point: 138.9 °C
• Appearance: /
• Density: 1.158 g/cm³
• CAS DataBase Reference: 2-AMINO-3-PHENYL-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-3-PHENYL-BUTYRIC ACID(2260-12-0)
• EPA Substance Registry System: 2-AMINO-3-PHENYL-BUTYRIC ACID(2260-12-0)

Safety Data

• Hazardous Substances Data: 2260-12-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-3-phenyl-butyric acid is utilized as a chiral building block for the synthesis of various drugs and compounds in the pharmaceutical industry. It is particularly valuable for the development of substances with potential analgesic and antioxidant properties.
Used in Neurological and Mood-Related Conditions:
2-Amino-3-phenyl-butyric acid is also being studied for its potential therapeutic applications in the treatment of neurological disorders and mood-related conditions, given its relationship with essential amino acids and neurotransmitters.

Upstream product

• 64230-80-4 2-bromo-3-phenyl-butyric acid 
• 859967-42-3 2-(N-nitroso-hydrazino)-3-phenyl-butyric acid methyl ester 
• 71564-77-7 bromo-(1-phenyl-ethyl)-malonic acid 
• 59850-50-9 diethyl (acetylamino)(1-phenylethyl)malonate 
• 585-71-7 (1-bromoethyl)benzne 

Downstream Products

• 25488-25-9 (2S,3S)-methylphenylalanine 
• 25488-26-0 erythro-D-(2R,3R)-β-methylphenylalanine 
• 59905-30-5 threo-D-(2R,3S)-β-methylphenylalanine 
• 64230-80-4 2-bromo-3-phenyl-butyric acid 
• 2643-78-9 (S)-2-amino-3(RS)-methyl-3-phenylpropioic acid 
• 137155-58-9 ethyl β-phenylaminobutyrate 
• 1214028-21-3 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylbutanoic acid 

Relevant articles and documents

Site-Selective γ-C(sp3)?H and γ-C(sp2)?H Arylation of Free Amino Esters Promoted by a Catalytic Transient Directing Group

The first selective PdII-catalysed γ-C(sp3)?H and γ-C(sp2)?H arylation of free amino esters using a commercially available catalytic transient directing group. A variety of free amino esters, including α-amino esters and β-amino esters, amino monoesters and amino bis-esters, are shown to react with a diverse range of simple aryl and heteroaryl iodide reagents.

Immunomodulatory peptides

The invention relates to peptides derivatized with a hydrophilic polymer which, in some embodiments, bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used in some embodiments, for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates, in further embodiments, to methods of using and methods of making the peptides of the invention.