22607-13-2

Basic information

• Product Name: 1,2-Butanediol, 1-phenyl
• Synonyms: 1,2-Butanediol, 1-phenyl;1-Phenyl-1,2-butanediol
• CAS NO: 22607-13-2
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 0
• Mol File: 22607-13-2.mol

Chemical Properties

• Boiling Point: 307.8°Cat760mmHg
• Flash Point: 148.8°C
• Appearance: /
• Density: 1.097g/cm³
• Vapor Pressure: 0.000306mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 1,2-Butanediol, 1-phenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Butanediol, 1-phenyl(22607-13-2)
• EPA Substance Registry System: 1,2-Butanediol, 1-phenyl(22607-13-2)

Safety Data

• Hazardous Substances Data: 22607-13-2(Hazardous Substances Data)

Usage

Physical state

Colorless and viscous liquid

Industrial applications

Solvent
Intermediate in organic synthesis
Pharmaceutical intermediate
Plasticizer
Precursor to the manufacturing of other chemicals

Uses

Production of polymers
Resins
Other organic compounds

Safety precautions

Harmful if ingested, inhaled, or comes into contact with the skin
Proper safety measures and protective equipment should be used when handling this compound

InChI:InChI=1/C10H14O2/c1-2-9(11)10(12)8-6-4-3-5-7-8/h3-7,9-12H,2H2,1H3

Upstream product

• 99359-49-6 (1,2-dibromo-butyl)-benzene 
• 33669-38-4 2-ethyl-3-phenyloxirane 
• 73951-64-1 cis-2-ethyl-3-phenyl-oxirane 
• 71-23-8 propan-1-ol 
• 100-52-7 benzaldehyde 
• 73951-65-2 trans-2-ethyl-3-phenyl-oxirane 
• 1005-64-7 trans-1-phenyl-1-butene 
• 1560-09-4 (Z)-but-1-en-1-ylbenzene 
• 21087-29-6 trans-3-phenylprop-2-enyl chloride 

Downstream Products

• 1007-32-5 benzyl ethyl ketone 

Relevant articles and documents

Biocatalytic single-step alkene cleavage from aryl alkenes: An enzymatic equivalent to reductive ozonization

(Chemical Equation Presented) O2 can do: Innocuous molecular oxygen O2 is the only reagent needed to perform highly chemoselective biocatalytic single-step alkene-cleavage reactions (see scheme). The products are analogous to those of (reductive) ozonization and related metal-based methods. In contrast neither special equipment nor an additional reducing agent is required. The biocatalytic reaction can be performed at ambient temperature. Depending on the substrate, aldehydes or ketones are obtained.

Novel self-coupling reaction of cyclic ketones under a high-pressure mercury lamp

A novel self-coupling reaction in alcohol or hexane-water of cycloalkanone (cycloheptanone, cyclooctanone, and cyclododecanone) with irradiation under a high-pressure mercury lamp yielded the corresponding pinacol-type compound in good yields. In the case of cyclohexanone, 2-methyl-, 2-phenyl-, 4-methylcyclohexanone, 5α- and 5β-cholestan-3-one, the pinacol derivatives were not obtained and the dimethyl acetals were given.

Enantioconvergent transformation of racemic cis-β-alkyl substituted styrene oxides to (R,R) threo diols by microsomal epoxide hydrolase catalysed hydrolysis

Both enantiomers of cis-β-ethyl, β-n-propyl, β-n-butyl, and β-n-hexyl substituted styrene oxides undergo microsomal epoxide hydrolase catalysed hydration at the (S) carbon to give the corresponding (R, R) threo diols in a > 90% e.e. A complete kinetic resolution of the racemic epoxide is also obtained with the β-ethyl substituted substrate, but not with its higher homologues.