23708-48-7

Basic information

• Product Name: PENTAMETHYLENEBIS(MAGNESIUM BROMIDE)
• Synonyms: PENTAMETHYLENEBIS(MAGNESIUM BROMIDE);PENTANE-1,5-DI(MAGNESIUM BROMIDE);Pentamethylenebis(magnesium bromide) solution;PENTAMETHYLENEBIS(MAGNESIUM BROMIDE), 0. 5M SOLUTION IN TETRAHYDROFURAN;Pentamethylenebis(magnesium bromide) solution 0.5 in THF;PentaMethylenebis(MagnesiuM broMide), 0.5M solution in THF, AcroSeal;Pentamethylenebis(magnesium bromide) 0.5M solution in THF;PentaMethylenebis(MagnesiuM broMide), 0.5M solution in THF, J&KSeal
• CAS NO: 23708-48-7
• Molecular Formula: C₅H₁₀Br₂Mg₂
• Molecular Weight: 278.55
• Product Categories: Alkyl;Chemical Synthesis;Grignard Reagents;Organometallic Reagents
• Mol File: 23708-48-7.mol

Chemical Properties

• Flash Point: 1 °F
• Appearance: Yellow to brown or gray/Solution
• Density: 0.999 g/mL at 25 °C
• CAS DataBase Reference: PENTAMETHYLENEBIS(MAGNESIUM BROMIDE)(CAS DataBase Reference)
• NIST Chemistry Reference: PENTAMETHYLENEBIS(MAGNESIUM BROMIDE)(23708-48-7)
• EPA Substance Registry System: PENTAMETHYLENEBIS(MAGNESIUM BROMIDE)(23708-48-7)

Safety Data

• Hazard Codes: F,C
• Statements: 11-14-19-34-40-37
• Safety Statements: 16-26-36/37/39-45
• RIDADR: UN 3399 4.3/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 23708-48-7(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Pentamethylenebis(magnesium bromide) is used as a building block for [various organic compounds] for [its unique chemical properties and reactivity in organic synthesis reactions]. It plays a crucial role in the formation of complex organic molecules and contributes to the development of new pharmaceuticals, materials, and chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Pentamethylenebis(magnesium bromide) is used as a key intermediate for [the synthesis of various drugs and drug candidates] for [its ability to form diverse organic compounds with potential therapeutic applications]. Its unique chemical properties make it a valuable asset in the development of novel drugs with improved efficacy and reduced side effects.
Used in Chemical Industry:
Pentamethylenebis(magnesium bromide) is used as a raw material for [the production of various chemicals and materials] for [its versatility in organic synthesis and ability to form a wide range of chemical products]. It is particularly useful in the synthesis of specialty chemicals, polymers, and other materials with specific properties and applications.
Used in Research and Development:
In the field of research and development, Pentamethylenebis(magnesium bromide) is used as a research compound for [exploring new reaction pathways and developing innovative synthetic methods] for [its unique reactivity and potential to yield novel organic compounds]. It serves as a valuable tool for chemists to study and understand complex reaction mechanisms and to design new synthetic strategies.

Upstream product

• 111-24-0 1,5-dibromo-pentane 
• 7439-95-4 magnesium 

Downstream Products

• 5445-24-9 1-n-propyl-1-cyclohexanol 
• 3302-83-8 1-phenylphosphinane 
• 4040-74-8 1,1-dimethyl-1-silacyclohexane 
• 13688-67-0 1,10-undecadiene 
• 54354-35-7 trans-1-(1-propenyl)cyclohexene 
• 462-94-2 1,5-diaminopentane 
• 18148-37-3 1-chloro-1-methyl-1-silacyclohexane 
• 1589-60-2 1-phenylcyclohexanol 
• 124620-30-0 1-phenethyl-cyclohexanol 
• 103169-56-8 mesityl-(2-pent-4-enyl-[1]naphthyl)-methanol 
• 103568-95-2 1,5-bis-[1-(2,4,6-trimethyl-benzoyl)-[2]naphthyl]-pentane 
• 30077-30-6 1-phenylarsinane 
• 18919-28-3 Si,Si,Si',Si'-tetraphenyl-Si,Si'-pentanediyl-bis-silane 
• 33493-90-2 (E)-1-(2-phenyl-1-ethenyl)cyclohexanol 

Relevant articles and documents

THE STRUCTURE OF 1,4-BISORGANOMAGNESIUM COMPOUNDS IN SOLUTION: 1,4-BIS(BROMOMAGNESIO)BUTANE AND (DIMERIC) MAGNESACYCLOPENTANE

1,4-Bis(bromomagnesio)butane (VI) and magnesacyclopentane (IV) were prepared and investigated as such and in combination with MgBr2 by measuring the degree of association in THF solution at three temperatures.It was established that IV does not exist as such, but is completely dimerized to 1,6-dimagnesacyclodecane (V).A Schlenk equilibrium is established between V and VI with K4(28.17 deg) = 100 +/- 50, K4(39.75 deg) = 250 +/- 100 and K4(48.84 deg) = 500 +/- 200 and the thermodynamic parameters ΔH4 = 15 kcal mol-1 and ΔS4 = 59 e.u..These values are veryclose to those of the higher homologue, 1,5-bis(bromomagnesio)pentane (III) and of ethylmagnesium bromide.It is concluded that these di-Grignard reagents behave essentially like the normal monovalent Grignard reagents.

METHOD FOR PRODUCING SILACYCLO MATERIALS

A method for producing silacycloalkanes by reacting an alkoxysilanc, R1ySi(OR2)4-y with a Grignard reagent, XMgR3MgX where each R1 is independently an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 2 to 4 carbon atoms, a hydrogen atom, or CF3 each R2 is independently an alkyl group having 1 to 4 carbon atoms; y has a value of 1 or 2; R3 is selected from an alkylene group having 1 to 10 carbon atoms; and X is a halogen.

Alkoxysilacycloalkanes, process for their preparation and their use for the polymerization of olefins

The invention relates to alkoxysilacycloalkanes, to the process of their preparation and to their use in the polymerization of olefins. The introduction of these alkoxysilacycloalkanes into the olefin polymerization environment makes it possible to raise the heptane-insolubles content of the polymer finally formed.

REACTIONS OF αω-BIS(BROMOMAGNESIO)ALKANES WITH HETEROCYCLIC ANHYDRIDES. A NOVEL SYNTHESIS OF FIVE AND SIX-MEMBERED 1-(o-AMINOPHENYL)CYCLOALKANOLS AND 1-(2'-AMINO-3'-PYRIDINYL)CYCLOALKANOLS

Isatoic anhydrides and azaisatoic anhydrides are converted by reaction with 1,4-bis(bromomagnesio)butane and 1,5-bis(bromomagnesio)pentane into the corresponding 1-(o-aminophenyl)cycloalkanols and 1-(2'-amino-3'pyridinyl)cycloalcanols.