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252367-34-3

ethyl 4-chloro-3-oxo-2-(2-phenylhydrazinylidene)butanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 252367-34-3 Structure

  • Basic information

    1. Product Name: ethyl 4-chloro-3-oxo-2-(2-phenylhydrazinylidene)butanoate
    2. Synonyms:
    3. CAS NO:252367-34-3
    4. Molecular Formula: C12H13ClN2O3
    5. Molecular Weight: 268.6962
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 252367-34-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 369.9°C at 760 mmHg
    3. Flash Point: 177.5°C
    4. Appearance: N/A
    5. Density: 1.24g/cm3
    6. Vapor Pressure: 1.15E-05mmHg at 25°C
    7. Refractive Index: 1.55
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: ethyl 4-chloro-3-oxo-2-(2-phenylhydrazinylidene)butanoate(CAS DataBase Reference)
    11. NIST Chemistry Reference: ethyl 4-chloro-3-oxo-2-(2-phenylhydrazinylidene)butanoate(252367-34-3)
    12. EPA Substance Registry System: ethyl 4-chloro-3-oxo-2-(2-phenylhydrazinylidene)butanoate(252367-34-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 252367-34-3(Hazardous Substances Data)

252367-34-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 252367-34-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,3,6 and 7 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 252367-34:
(8*2)+(7*5)+(6*2)+(5*3)+(4*6)+(3*7)+(2*3)+(1*4)=133
133 % 10 = 3
So 252367-34-3 is a valid CAS Registry Number.

252367-34-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4-chloro-3-oxo-2-(phenylhydrazinylidene)butanoate

1.2 Other means of identification

Product number -
Other names 4-chloro-3-oxo-2-(phenylhydrazono)butyric acid ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:252367-34-3 SDS

252367-34-3Relevant articles and documents

Synthesis of 2-arylhydrazono-4-chloro-3-oxobutanoates existing as (E)/(Z)-hydrazone isomers in solution: Correlation between equilibrium constants and substituent constants

Kawamura, Chihaya,Yoshida, Kiminari,Yamazaki, Naoki,Sato, Noriko,Nagai, Kenichiro,Kaji, Eisuke,Kurasawa, Yoshihisa

, (2020)

Various 2-arylhydrazono-4-chloro-3-oxobutanoates 10a-i synthesized by the reaction of ethyl 4-chloro-3-oxobutanoate with the 4-substituted benzenediazonium chlorides were found to exist as two isomers between the (E)- and (Z)-hydrazone forms in DMSO?dsub

Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL)

Breinbauer, Rolf,Doler, Carina,Fuchs, Elisabeth,Grabner, Gernot F.,Mayer, Nicole,Melcher, Michaela-Christina,Migglautsch, Anna K.,Romauch, Matthias,Schweiger, Martina,Zechner, Rudolf,Zimmermann, Robert

supporting information, (2020/07/13)

High serum fatty acid (FA) levels are causally linked to the development of insulin resistance, which eventually progresses to type 2 diabetes and non-alcoholic fatty liver disease (NAFLD) generalized in the term metabolic syndrome. Adipose triglyceride lipase (ATGL) is the initial enzyme in the hydrolysis of intracellular triacylglycerol (TG) stores, liberating fatty acids that are released from adipocytes into the circulation. Hence, ATGL-specific inhibitors have the potential to lower circulating FA concentrations, and counteract the development of insulin resistance and NAFLD. In this article, we report about structure–activity relationship (SAR) studies of small molecule inhibitors of murine ATGL which led to the development of Atglistatin. Atglistatin is a specific inhibitor of murine ATGL, which has proven useful for the validation of ATGL as a potential drug target.

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