261165-05-3 Usage
Uses
Used in Pharmaceutical Industry:
(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID is used as a reagent for the synthesis of 3-substituted aminocyclopentanes, which are potent NR2B subtype-selective NMDA antagonists. These antagonists are being developed for the treatment of neuropathic pain and Parkinson's disease, as they can modulate the activity of the NMDA receptor, a key player in neuronal function and synaptic plasticity.
Additionally, due to its unique structure and properties, (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID may also be utilized in other applications within the pharmaceutical industry, such as the development of novel drugs targeting different receptors or enzymes, or as a building block for the creation of complex organic molecules with potential therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 261165-05-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,1,1,6 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 261165-05:
(8*2)+(7*6)+(6*1)+(5*1)+(4*6)+(3*5)+(2*0)+(1*5)=113
113 % 10 = 3
So 261165-05-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H19NO4/c1-11(2,3)16-10(15)12-8-5-4-7(6-8)9(13)14/h7-8H,4-6H2,1-3H3,(H,12,15)(H,13,14)/p-1/t7-,8+/m0/s1
261165-05-3Relevant articles and documents
Inhibitors of protein kinases
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, (2011/10/04)
Compounds of general Formula (I): wherein R1, R2, R3, Ra, A, B and x are as defined herein are inhibitors of protein kinases in particular members of the cyclin-dependent kinase family and/or the glycogen synthase kinase 3 family and are useful in preventing and/or treating any type of pain, inflammatory disorders, cancer, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases, metabolic disorders, renal diseases, neurologic and neuropsychiatric diseases and neurodegenerative diseases.
Methyl-blocked dimeric α,γ-peptide nanotube segments: Formation of a peptide heterodimer through backbone-backbone interactions
Brea, Roberto J.,Amorin, Manuel,Castedo, Luis,Granja, Juan R.
, p. 5710 - 5713 (2007/10/03)
Cyclic peptides can dimerize through β-sheet-like hydrogen bonding. Heterodimerization is favored over homodimerization, which creates interesting combinatorial possibilities without detriment to the functionalization of amino acid side chains. These dime
