489446-72-2

Usage

Uses

Used in Organic Synthesis:
Cyclopentanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,3R)is used as a key intermediate in organic synthesis for the development of novel compounds with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Cyclopentanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,3R)is used as a building block for the synthesis of new drug candidates. Its unique structure and stereochemistry may contribute to the discovery of innovative therapeutic agents with improved efficacy and selectivity.
Used in Medicinal Chemistry:
Cyclopentanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,3R)is utilized in medicinal chemistry for the design and optimization of bioactive molecules. Its specific structural features and stereochemistry can influence the compound's binding affinity, selectivity, and pharmacokinetic properties, leading to the development of more effective and safer drugs.
Overall, the specific nature of Cyclopentanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,3R)-'s structure and configuration make it an interesting target for further research and development in various scientific and industrial contexts. Its potential applications in organic synthesis, pharmaceuticals, and medicinal chemistry highlight the importance of exploring and understanding the properties of such unique chemical compounds.

Upstream product

• 554451-12-6 (1S,3R)-3-tert-butoxycarbonylamino-cyclopentanecarboxylic acid methyl ester 
• 67-56-1 methanol 
• 489446-85-7 (1R,3R)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid 
• 130931-83-8 (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 200002-41-1 (-)-[(1R,4S)-tert-butyl 3-oxo-2-azabicyclo(2.2.1)hept-5-ene-2-carboxylate] 
• 693245-53-3 tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate 
• 124-41-4 sodium methylate 
• 74-88-4 methyl iodide 
• 261165-05-3 (1S,3R)-3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid 

Downstream Products

• 1203306-05-1 (1R,3R)-3-aminocyclopentane-1-carboxylic acid hydrochloride 
• 884006-56-8 (1R,3R)-3-N-BOC-aminocyclopentylmethanol 
• 180323-49-3 (1S,3R)-methyl 3-aminocyclopentanecarboxylate hydrochloride 
• 489446-85-7 (1R,3R)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid 

Relevant academic research and scientific papers

HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

PYRAZOLO-PYRIMIDIN-AMINO-CYCLOALKYL COMPOUNDS AND THEIR THERAPEUTIC USES

Disclosed herein are pyrazolo-pyrimid in-ami no-cycloalkyl compounds, analogs thereof, pharmaceutical compositions comprising thereof and therapeutic uses therefor.

COMPLEMENT PATHWAY MODULATORS AND USES THEREOF

The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION

The present invention relates to novel compounds useful as dipeptidyl peptidase IV (DPP-IV) inhibitors of the formula: (I) wherein Y is -S(O)m, -CH2-, CHF, or -CF2; m is 0, 1, or 2; X is a bond, C1-C5 alkyl (e.g., -CH2-), or -C(=0)-; the dotted line [----] in the carbocyclic ring represents an optional double bond; R1 is substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkylalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclic ring, substituted or unsubstituted heterocyclylalkyl, substituted or unsubstituted heteroarylalkyl, CN, -COOR3, CONR3R4, -OR3, -NR3R4, or NR3COR3; R2 is hydrogen, cyano, COOH, or an isostere of a carboxylic acid (such as SO3H, CONOH, B(OH)2, PO3R3R4, SO2NR3R4, tetrazole, -COOR3, -CONR3R4, NR3COR4, or -COOCOR3).