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O-Benzyl Psilocin is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 28383-23-5 Structure
  • Basic information

    1. Product Name: O-Benzyl Psilocin
    2. Synonyms: O-Benzyl Psilocin;4-(Benzyloxy)-3-[2-(diMethylaMino)ethyl]indole;4-(Benzyloxy)-N,N-diMethyltryptaMine;N,N-DiMethyl-4-(phenylMethoxy)-1H-indole-3-ethanaMine;2-(4-(benzyloxy)-1H-indol-3-yl)-N,N-dimethylethanamine(WXG00095)
    3. CAS NO:28383-23-5
    4. Molecular Formula: C19H22N2O
    5. Molecular Weight: 293.38284
    6. EINECS: N/A
    7. Product Categories: Indole Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Indole Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 28383-23-5.mol
  • Chemical Properties

    1. Melting Point: 87-88 °C
    2. Boiling Point: 472.9±40.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.133±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C, Inert atmosphere
    8. Solubility: DMSO (Slightly), Methanol (Slightly)
    9. PKA: 17.41±0.30(Predicted)
    10. CAS DataBase Reference: O-Benzyl Psilocin(CAS DataBase Reference)
    11. NIST Chemistry Reference: O-Benzyl Psilocin(28383-23-5)
    12. EPA Substance Registry System: O-Benzyl Psilocin(28383-23-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 28383-23-5(Hazardous Substances Data)

28383-23-5 Usage

Uses

Protected precursor to Psilocin.

Check Digit Verification of cas no

The CAS Registry Mumber 28383-23-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,3,8 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 28383-23:
(7*2)+(6*8)+(5*3)+(4*8)+(3*3)+(2*2)+(1*3)=125
125 % 10 = 5
So 28383-23-5 is a valid CAS Registry Number.

28383-23-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name O-Benzyl Psilocin

1.2 Other means of identification

Product number -
Other names N,N-dimethyl-2-(4-phenylmethoxy-1H-indol-3-yl)ethanamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28383-23-5 SDS

28383-23-5Relevant articles and documents

3-(2-(AMINOETHYL)-INDOL-4-OL DERIVATIVES, METHODS OF PREPARATION THEREOF, AND THE USE AS 5-HT2 RECEPTOR MODULATORS

-

, (2021/09/17)

A compound of Formula I, which possesses 5-HT2A and/or 5-HT2c selective receptor activity, but lacks at least some of the undesirable characteristics of 5-HT2B-agonist related activities, is disclosed. Methods of preparing said compo

Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: Synthesis of psilocin, bufotenin, and serotonin

Bartolucci, Silvia,Mari, Michele,Di Gregorio, Giovanni,Piersanti, Giovanni

, p. 2233 - 2238 (2016/04/19)

Observations concerning the synthesis of substituted tryptamine derivatives starting from indoles and 1,n-amino alcohols via the borrowing hydrogen process are discussed. This catalytic, single-step, and modular approach to tryptamines and homotryptamines allows the synthesis of branched and nonbranched tryptamines as well as tryptamine-based natural products such as psilocin, bufotenin, and serotonin.

SAR of psilocybin analogs: Discovery of a selective 5-HT2C agonist

Sard, Howard,Kumaran, Govindaraj,Morency, Cynthia,Roth, Bryan L.,Toth, Beth Ann,He, Ping,Shuster, Louis

, p. 4555 - 4559 (2007/10/03)

An SAR study of psilocybin and psilocin derivatives reveals that 1-methylpsilocin is a selective agonist at the h5-HT2C receptor. The corresponding phosphate derivative, 1-methylpsilocybin, shows efficacy in an animal model for obsessive-compul

Improvements to the synthesis of psilocybin and a facile method for preparing the O-acetyl prodrug of psilocin

Nichols, David E.,Frescas, Stewart

, p. 935 - 938 (2007/10/03)

An improved procedure to accomplish the O-phosphorylation of 4-hydroxy- N,N-dimethyltryptamine (psilocin 5) is reported that utilizes reaction between the O-lithium salt of 5 and tetra-O-benzylpyrophosphate. The O- benzyl groups were removed by catalytic hydrogenation over palladium on carbon to afford N,N-dimethyl-4-phosphoryloxytryptamine (psilocybin, 1). In view of difficulties encountered in the preparation of 1, it is suggested that 4-acetoxy-N,N-dimethyltryptamine (2) may be a useful alternative for pharmacological studies. The latter was obtained following catalytic O- debenzylation of 4-benzyloxy-N,N-dimethyltryptamine in the presence of acetic anhydride and sodium acetate.

A five-step synthesis of psilocin from indole-3-carbaldehyde

Yamada, Fumio,Tamura, Mayumi,Somei, Masanori

, p. 451 - 457 (2007/10/03)

A novel preparative method of psilocin was established in only five steps from indole-3-carbaldehyde in 50% overall yield.

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