3080-97-5

Basic information

• Product Name: N,N'-dicinnamylideneethylenediamine
• Synonyms: N,N'-Bis(3-phenyl-2-propene-1-ylidene)ethylenediamine;N,N'-Bis(3-phenyl-2-propenylidene)-1,2-ethanediamine;N,N'-Bis(3-phenylallylidene)ethylenediamine;N,N'-Ethylenebis(3-phenyl-2-propene-1-imine);Einecs 221-373-8
• CAS NO: 3080-97-5
• Molecular Formula: C₂₀H₂₀N₂
• Molecular Weight: 288.39
• EINECS: 221-373-8
• Mol File: 3080-97-5.mol

Chemical Properties

• Boiling Point: 474.5°Cat760mmHg
• Flash Point: 233.6°C
• Appearance: /
• Density: 0.93g/cm³
• CAS DataBase Reference: N,N'-dicinnamylideneethylenediamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-dicinnamylideneethylenediamine(3080-97-5)
• EPA Substance Registry System: N,N'-dicinnamylideneethylenediamine(3080-97-5)

Safety Data

• Hazardous Substances Data: 3080-97-5(Hazardous Substances Data)

Upstream product

• 107-15-3 ethylenediamine 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 24808-79-5 (E)-2-(3-phenylprop-2-en-1-ylidene)indane-1,3-dione 

Relevant articles and documents

Impaired ergosterol biosynthesis mediated fungicidal activity of Co(II) complex with ligand derived from cinnamaldehyde

In this study, we have used aldehyde function of cinnamaldehyde to synthesize N, N′-Bis (cinnamaldehyde) ethylenediimine [C20H20N2] and Co(II) complex of the type [Co(C40H40N4)Cl2]. The structures of the synthesized compounds were determined on the basis of physiochemical analysis and spectroscopic data (1H NMR, FTIR, UV-visible and mass spectra) along with molar conductivity measurements. Anticandidal activity of cinnamaldehyde its ligand [L] and Co(II) complex was investigated by determining MIC80, time-kill kinetics, disc diffusion assay and ergosterol extraction and estimation assay. Ligand [L] and Co(II) complex are found to be 4.55 and 21.0 folds more efficient than cinnamaldehyde in a liquid medium. MIC80 of Co(II) complex correlated well with ergosterol inhibition suggesting ergosterol biosynthesis to be the primary site of action. In comparison to fluconazole, the test compounds showed limited toxicity against H9c2 rat cardiac myoblasts. In confocal microscopy propidium iodide (PI) penetrates the yeast cells when treated with MIC of metal complex, indicating a disruption of cell membrane that results in imbibition of dye. TEM analysis of metal complex treated cells exhibited notable alterations or damage to the cell membrane and the cell wall. The structural disorganization within the cell cytoplasm was noted. It was concluded that fungicidal activity of Co(II) complex originated from loss of membrane integrity and a decrease in ergosterol content is only one consequence of this.

Microwave-assisted efficient synthesis of diimines in dry media using silica gel supported sodium hydrogen sulfate as reusable solid support

A simple and efficient method for synthesis of diimines using silica gel supported sodium hydrogen sulfate as reusable solid support in solvent-free conditions under microwave irradiation is described.

Stereoselective synthesis of cis-bis-β-lactams linked with an ethylene bridge

An efficient synthesis of (±)-cis-bis-β-lactams (5 and 6) via cycloaddition reaction of bisimines (3a-c) with acid chlorides (4) in the presence of triethylamine in very good yield is described. (C) 2000 Published by Elsevier Science Ltd.