313483-17-9

Basic information

• Product Name: 1-(3,4-dimethylphenyl)-2-methyl-5-phenyl-1H-pyrrole
• Synonyms: 1-(3,4-dimethylphenyl)-2-methyl-5-phenyl-1H-pyrrole
• CAS NO: 313483-17-9
• Molecular Formula: C19H19N
• Molecular Weight: 261.36086
• Mol File: 313483-17-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3,4-dimethylphenyl)-2-methyl-5-phenyl-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dimethylphenyl)-2-methyl-5-phenyl-1H-pyrrole(313483-17-9)
• EPA Substance Registry System: 1-(3,4-dimethylphenyl)-2-methyl-5-phenyl-1H-pyrrole(313483-17-9)

Safety Data

• Hazardous Substances Data: 313483-17-9(Hazardous Substances Data)

Upstream product

• 95-64-7 4-amino-o-xylene 
• 583-05-1 1-phenylpentane-1,4-dione 
• 100-42-5 styrene 
• 100-52-7 benzaldehyde 

Relevant articles and documents

A fluorescent target-guided Paal-Knorr reaction

It has become increasingly apparent that high-diversity chemical reactions play a significant role in the discovery of bioactive small molecules. Here, we describe an expanse of this paradigm, combining a ‘target-guided synthesis’ concept with Paal-Knorr chemistry applied to the preparation of fluorescent ligands for human prostaglandin-endoperoxide synthase (COX-2).

One-pot synthesis of 2-methyl-1,5-diaromatic-1H-pyrroles from styrene, acetone and arylamines using TBHP, copper(II) trifluoromethanesulfonate and sulfamic acid

The one-pot copper/manganese co-catalyzed heterocyclization of arylamine derivatives with styrene and acetone to produce a series of 2-methyl-1,5-diaromatic-1H-pyrroles was investigated. The described reaction combines 1,4-dicarbonyl synthesis and Paal-Knorr type condensation reactions.