321840-52-2 Usage
Uses
Used in Pharmaceutical Research and Development:
(1s)-1-(4-fluorophenyl)butylamine-hcl is used as a precursor or intermediate in the synthesis of pharmaceutical compounds for the treatment of neurological disorders and mental health conditions. Its unique structure allows for the development of new drugs with potential therapeutic effects on these conditions.
Used in Organic Synthesis:
In the field of organic synthesis, (1s)-1-(4-fluorophenyl)butylamine-hcl serves as a building block for the creation of new compounds with potential pharmaceutical properties. Its versatility in chemical reactions enables the synthesis of a wide range of organic compounds with diverse applications.
Used in Research Applications:
(1s)-1-(4-fluorophenyl)butylamine-hcl is used in research settings to study the properties and potential applications of this compound and its derivatives. Its enhanced solubility in aqueous solutions, due to the hydrochloride salt form, makes it suitable for various research applications, including the investigation of its chemical reactivity, stability, and interactions with other molecules.
Used in Drug Delivery Systems:
The hydrochloride salt form of (1s)-1-(4-fluorophenyl)butylamine-hcl allows for easier handling and storage of the compound, making it a suitable candidate for drug delivery systems. Its enhanced solubility in aqueous solutions can improve the bioavailability and therapeutic outcomes of drugs synthesized using this compound as a precursor or intermediate.
Check Digit Verification of cas no
The CAS Registry Mumber 321840-52-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,1,8,4 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 321840-52:
(8*3)+(7*2)+(6*1)+(5*8)+(4*4)+(3*0)+(2*5)+(1*2)=112
112 % 10 = 2
So 321840-52-2 is a valid CAS Registry Number.
321840-52-2Relevant articles and documents
METALLOENZYME INHIBITOR COMPOUNDS
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, (2018/09/28)
Provided are compounds having HDAC6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by HDAC6.
Synthesis of enantiopure 1-aryl-1-butylamines and 1-aryl-3-butenylamines by diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide
Dalmolen, Jan,Van Der Sluis, Marcel,Nieuwenhuijzen, Jose W.,Meetsma, Auke,De Lange, Ben,Kaptein, Bernard,Kellogg, Richard M.,Broxterman, Quirinus B.
, p. 1544 - 1557 (2007/10/03)
The synthesis of enantiopure 1-aryl-1-butylamines via a highly diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide is reported. These are synthesised by a three-step procedure, which involves: (a) formation of the chiral imines; (b) asymmetric addition of the allylzinc reagent; (c) removal of the chiral auxiliary by means of a reductive or non-reductive method. The reductive method provides 1-aryl-1-butylamines whereas the non-reductive method preserves the double bond to afford 1-aryl-3-butenylamines. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
Synthesis of optically-active benzylic amines; asymmetric reduction of ketoxime ethers with chiral oxazaborolidines
Fontaine, Evelyne,Namane, Claudie,Meneyrol, Jerome,Geslin, Michel,Serva, Laurence,Roussey, Eliane,Tissandie, Stephanie,Maftouh, Mohamed,Roger, Pierre
, p. 2185 - 2189 (2007/10/03)
The preparation of novel optically active benzylic amines by the enantioselective reduction of phenone oximes using chiral oxazaborolidine is described. The choice of the chiral 1,2-amino alcohol (S)-diphenylvalinol as chiral inducer and that of the benzy