327101-25-7Relevant articles and documents
(Bromodimethyl)sulfonium bromide: An inexpensive reagent for the solvent-free, one-pot synthesis of α-aminophosphonates
Kudrimoti, Sucheta,Rao Bommena, Vittal
, p. 1209 - 1210 (2005)
A novel solvent-free, one-pot synthesis of α-aminophosphonates in the presence of catalytic (bromodimethyl)sulfonium bromide at room temperature in high yields is reported.
CAL-B accelerated novel synthetic protocols for 3,3’-arylidenebis-4-hydroxycoumarins and dimethyl ((substituted phenyl) (phenylamino)methyl) phosphonates
Chavan, Anusaya S.,Kharat, Arun S.,Bhosle, Manisha R.,Dhumal, Sambhaji T.,Mane, Ramrao A.
, p. 4497 - 4512 (2021/07/26)
Green protocols for the syntheses of 3,3′-arylidenebis-4-hydroxycoumarins and dimethyl ((substituted phenyl) (phenylamino)methyl) phosphonates have been first time developed using biocatalyst, CAL-B (lipase). These are carried at room temperature under st
Design and preparation of HPW-anchored magnetic carbon nitride nanosheets: an efficient and eco-friendly nanocomposite for one-pot synthesis of α-amino phosphonates
Azhdari, Asieh,Azizi, Najmedin
, p. 4915 - 4928 (2021/07/28)
Heterogeneous catalysis is one of the fastest and greatest developing branches and longstanding challenges in academic researchers and the chemical industry. Carbon-based material with various functional groups, the most abundant elements, and the main component in natural products provide a unique platform for heterogeneous catalysis due to their excellent biocompatibility and high performance. Herein, we introduce a novel nanocomposite comprising of different acids anchored to magnetic mesoporous carbon nitrides through a grindstone method to enhance nanocomposite catalysts’ environmentally benign capability. As a result, the obtained porous magnetic catalysts show the highest possible activity and product selectivity for facile preparation of α-amino phosphonates derivatives in good to excellent yields at ambient temperature. This fast and straightforward methodology offers pot economy for the satisfactory reaction of various aldehyde, amine, and triaryl and trialkyl phosphite with a broad range of functional groups in a gram scale under mild reaction conditions.
Formic acid catalyzed one-pot synthesis of α-aminophosphonates: an efficient, inexpensive and environmental friendly organocatalyst
Azarnia Mehraban, Jamshid,Jalali, Mahsa Sadat,Heydari, Akbar
, p. 2215 - 2223 (2018/08/04)
Abstract: Aqueous formic acid is used for the synthesis of α-aminophosphonates through Kabachnik–Fields reaction applying aromatic amine, phosphite, and carbonyl compounds. Using formic acid as an efficient and low-cost organocatalyst provides environmental friendly, high yields, low reaction time and mild reaction condition. The isolated products were analyzed by IR, NMR, and mass techniques. Graphical abstract: [Figure not available: see fulltext.].
A new procedure for synthesis of α -aminophosphonates by aqueous formic acid as an effective and environment-friendly organocatalyst
Mohammadiyan, Esmaeil,Ghafuri, Hossein,Kakanejadifard, Ali
, p. 1883 - 1891 (2017/12/15)
Abstract: Aqueous formic acid (37%) as a green organocatalyst was used to synthesis of α -aminophosphonates in one-pot, three-component Kabachnik–Fields reaction. The structures of compounds were determined by FT-IR, 1H -NMR and 13C -NMR spectroscopy. After optimization of the experimental?conditions, the reaction was carried out at 65°C under solvent- free condition. Use of a nontoxic effective organocatalyst, easy work up process and low-cost cleaning procedure are from the main advantages of this research. Graphical Abstract: Synthesis and characterization of α -aminophosphonates in one-pot, three-component Kabachnik–Fields reaction by formic acid in solvent free condition are reported. Using of a nontoxic effective organocatalyst, easy work up process and low-cost cleaning procedure are from the main advantages of this research.
Synthesis of α-aminophosphonates in the presence of triethylammonium hydrogen sulfate [Et3NH][HSO4] as a highly efficient ionic liquid catalyst
Karimi-Jaberi, Zahed,Bazyar, Ladan,Amiri, Mohammad
, p. 23 - 26 (2017/07/22)
Triethylammonium hydrogen sulfate was used as a cheap and mild acidic ionic liquid for efficient, one-pot, three-component reaction of aldehydes, amines and trimethyl phosphite. Thus α-aminophosphonates were synthesized at room temperature in excellent yields. The ionic liquid catalyst is air and water stable, easy to prepare from amine and acid and easily separated from the reaction mixture. (Chemical Equation Presented).
Highly efficient synthesis of α-aminophosphonates catalyzed by hafnium(IV) chloride
Li, Xiao-Chuan,Gong, Shan-Shan,Zeng, De-Yun,You, Yue-Hai,Sun, Qi
supporting information, p. 1782 - 1785 (2016/04/05)
A highly efficient one-pot method for the synthesis of a variety of α-aminophosphonates via the one-pot three-component reaction of aldehyde, amine, and phosphite has been developed using only 2 mol % HfCl4 as the catalyst. The NMR evidence strongly indicated the catalytic roles of Hf(IV) on the activation of aldehyde, phosphite, and imine intermediate.
Highly efficient solvent free synthesis of α-aminophosphonates catalyzed by recyclable nano-magnetic sulfated zirconia (Fe3O4@ZrO2/SO42-)
Ghafuri, Hossein,Rashidizadeh, Afsaneh,Esmaili Zand, Hamid Reza
, p. 16046 - 16054 (2016/02/19)
In this project, nano-magnetic sulfated zirconia Fe3O4@ZrO2/SO42- was prepared and characterized using various instrumental methods. Sulfated zirconia supported on magnetic nanoparticles can act as a well-organized nanocatalyst and can be easily separated from the reaction mixture using an external magnetic field. Nano-Fe3O4@ZrO2/SO42- is a heterogeneous acidic catalyst and has particular advantages such as a facile synthesis procedure, high activity, easy separation and reusability. It was applied as an efficient nanocatalyst in the synthesis of α-aminophosphonate derivatives in the Kabachnik-Fields reaction. This synthetic method has several advantages including high yields, short reaction times, easy workup and environmentally benign reaction conditions.
Graphene Oxide as Recyclable Catalyst for One-Pot Synthesis of α-Aminophosphonates
Dhopte, Kiran B.,Raut, Dnyaneshwar S.,Patwardhan, Anand V.,Nemade, Parag R.
, p. 788 - 798 (2015/10/29)
We report the synthesis of α-aminophosphonates from aromatic aldehydes, aromatic and aliphatic amines, and trimethylphosphite (Kabachnik-Fields reaction) using a "carbocatalyst," graphene oxide, at room temperature with excellent yield and recyclability. Enhanced catalytic activity of graphene oxide as compared to other catalysts studied is possibly due to the presence of carboxylic acid and hydroxyl groups. GRAPHICAL ABSTRACT.
A catalyst-free synthesis of α-aminophosphonates in glycerol
Azizi, Kobra,Karimi, Meghdad,Heydari, Akbar
, p. 7236 - 7239 (2015/01/09)
A simple and efficient method is described using glycerol as a solvent in the catalyst-free synthesis of α-aminophosphonates in high purity. Products are prepared by the Kabachnik-Fields reaction from amines, phosphites, and carbonyl compounds. The method does not require a toxic catalyst.
