34086-50-5Relevant articles and documents
Preparation method of isoflavone compounds
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Paragraph 0035; 0037; 0039-0040; 0051; 0053; 0055, (2019/10/10)
The invention belongs to the technical field of medicine, and particularly discloses a preparation method of isoflavone compounds. The structures of the compounds are shown in the formula I and the formula II. According to the preparation method, genistei
Indonesian medicinal plants. XXI. Inhibitors of Na+/H+ exchanger from the bark of Erythrina variegata and the roots of Maclura cochinchinensis
Kobayashi, Motomasa,Mahmud, Taifo,Yoshioka, Naoki,Shibuya, Hirotaka,Kitagawa, Isao
, p. 1615 - 1619 (2007/10/03)
Through bioassay-guided separation of the methanol extracts of Indonesian medicinal plants, three inhibitors of the Na+/H+ exchange system, erythrinin B (2), euchrenone b10 (3), and 1,3,5-trihydroxy-4-(3- methylbut-2-enyl)xanthen-9-one (4), were isolated from the bark of Erythrina variegata (Fabaceae) (for 2) and the roots of Maclura cochinchinensis (Moraceae) (for 2, 3, 4). Compounds 2, 3, and 4 significantly inhibited the Na+/H+ exchange system of arterial smooth muscle cells, with minimum inhibitory concentrations of 1.25, 1.25, and 10 μg/ml, respectively. Three new prenylated xanthones named isocudraniaxanthones B (5) and A (7) and isoalvaxanthone (9) were also isolated from M. cochinchinensis and the chemical structures were elucidated on the bases of their chemical and physicochemical properties.
SYNTHESIS OF 4',5- AND 3',4',5-OXYGENATED PYRANOISOFLAVONES: ALPINUM ISOFLAVONE AND RELATED COMPOUNDS, AND REVISED STRUCTURE OF DERRONE
Tsukayama, Masao,Kawamura, Yasuhiko,Tahara, Hideo
, p. 505 - 516 (2007/10/02)
Alpinumisoflavone (4',5-dihydroxy-2",2"-dimethylpyranoisoflavone) (1a) was synthesized by regioselective reduction of 7-(4-hydroxyphenyl)-2,3-dihydro-5-methoxy-2,2-dimethyl-4H,6H-benzodipyran-4,6-dione (15a) with NaBH4 and dehydrati
SYNTHESIS OF ALPINUM ISOFLAVONE, DERRONE AND RELATED PYRANOISOFLAVONES
Rao, K. S. R. Mohan,Iyer, C. S. Rukmani,Iyer, P. R.
, p. 3015 - 3020 (2007/10/02)
Reaction of phenacylchroman 1 with ethoxyalyl chloride in pyridine followed by hydrolysis of the resulting esters 2 and 3 and decarboxylation of the acids 4 and 5, gave dihydro-4'-O-methyl alpinum isoflavone 6 and 4'-O-methylderrone 7 respectively.Similarly 8 gave 11 which was selectively demethylated to 7.DDQ, dehydrogenation of 6, 7 and 11 gave 14, 15 and 17.Demethylation of 6 and 7 followed by dehydrogenation gave alpinum isoflavone 18 and derrone 19.