34086-50-5

Basic information

• Product Name: alpinumisoflavone
• Synonyms: alpinumisoflavone;5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one
• CAS NO: 34086-50-5
• Molecular Formula: C₂₀H₁₆O₅
• Molecular Weight: 336.33804
• Mol File: 34086-50-5.mol

Chemical Properties

• Boiling Point: 562.1°Cat760mmHg
• Flash Point: 205.8°C
• Appearance: /
• Density: 1.368g/cm³
• Vapor Pressure: 3.06E-13mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: alpinumisoflavone(CAS DataBase Reference)
• NIST Chemistry Reference: alpinumisoflavone(34086-50-5)
• EPA Substance Registry System: alpinumisoflavone(34086-50-5)

Safety Data

• Hazardous Substances Data: 34086-50-5(Hazardous Substances Data)

Usage

Definition

ChEBI: A natural product found in Ficus mucuso.

InChI:InChI=1/C20H16O5/c1-20(2)8-7-13-15(25-20)9-16-17(18(13)22)19(23)14(10-24-16)11-3-5-12(21)6-4-11/h3-10,21-22H,1-2H3

Upstream product

• 63807-90-9 5-hydroxy-3(4'-hydroxy)phenyl-8,8-dimethyl-6,7-dihydro-4H,8H-benzo<1,2b:5,4b'>dipyran-4-one 
• 51225-30-0 erythrinin B 
• 114090-97-0 2-carbethoxy-5-hydroxy-3-(4'-methoxy)phenyl-8,8-dimethyl-6,7-dihydro-4H,8H-benzo<1,2b:5,4b'>dipyran-4-one 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 446-72-0 5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on 
• 114090-99-2 5-hydroxy-3-(4'-methoxy)phenyl-8,8-dimethyl-6,7-dihydro-4H,8H-benzo<1,2b:5,4b'>dipyran-4-one-2-carboxylic acid 
• 57261-40-2 1-(5,7-Dihydroxy-2,2-dimethyl-chroman-6-yl)-2-(4-methoxy-phenyl)-ethanone 
• 27763-00-4 5-hydroxy-3-(4'-methoxy3)phenyl-8,8-dimethyl-6,7-dihydro-4H,8H-benzo<1,2b:5,4b'>dipyran-4-one 
• 141737-71-5 7-Benzyloxy-6-[(E)-3-(4-benzyloxy-phenyl)-acryloyl]-5-methoxy-2,2-dimethyl-chroman-4-one 
• 141737-59-9 6-[(E)-3-(4-Benzyloxy-phenyl)-acryloyl]-7-hydroxy-5-methoxy-2,2-dimethyl-chroman-4-one 
• 141737-74-8 7-(4-hydroxyphenyl)-2,3-dihydro-5-methoxy-2,2-dimethyl-4H,6H-benzo<1,2-b:5,4-b'>dipyran-4,6-dione 
• 141737-80-6 6-Hydroxy-3-(4-hydroxy-phenyl)-5-methoxy-8,8-dimethyl-7,8-dihydro-6H-pyrano[3,2-g]chromen-4-one 
• 124360-59-4 6-acetyl-7-hydroxy-5-methoxy-2,2-dimethyl-4-chromanone 
• 141737-82-8 4'-hydroxy-5-methoxy-2'',2''-dimethylpyrano[5'',6'':6,7]isoflavone 

Downstream Products

• 27762-87-4 5-hydroxy-3(4'-methoxy)phenyl-8,8-dimethyl-4H,8H-benzo<1,2b:5,4b'>dipyran-4-one 
• 34086-56-1 5-methoxy-7-(4-methoxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']-dipyran-6-one 
• 51472-54-9 5-acetoxy-3-(4-acetoxy-phenyl)-8,8-dimethyl-8H-pyrano[3,2-g]chromen-4-one 
• 86989-18-6 Acetic acid 4-(5-hydroxy-8,8-dimethyl-4-oxo-4H,8H-pyrano[3,2-g]chromen-3-yl)-phenyl ester 
• 4449-55-2 scandenone 

Relevant articles and documents

Preparation method of isoflavone compounds

The invention belongs to the technical field of medicine, and particularly discloses a preparation method of isoflavone compounds. The structures of the compounds are shown in the formula I and the formula II. According to the preparation method, genistei

Indonesian medicinal plants. XXI. Inhibitors of Na+/H+ exchanger from the bark of Erythrina variegata and the roots of Maclura cochinchinensis

Through bioassay-guided separation of the methanol extracts of Indonesian medicinal plants, three inhibitors of the Na+/H+ exchange system, erythrinin B (2), euchrenone b10 (3), and 1,3,5-trihydroxy-4-(3- methylbut-2-enyl)xanthen-9-one (4), were isolated from the bark of Erythrina variegata (Fabaceae) (for 2) and the roots of Maclura cochinchinensis (Moraceae) (for 2, 3, 4). Compounds 2, 3, and 4 significantly inhibited the Na+/H+ exchange system of arterial smooth muscle cells, with minimum inhibitory concentrations of 1.25, 1.25, and 10 μg/ml, respectively. Three new prenylated xanthones named isocudraniaxanthones B (5) and A (7) and isoalvaxanthone (9) were also isolated from M. cochinchinensis and the chemical structures were elucidated on the bases of their chemical and physicochemical properties.

SYNTHESIS OF 4',5- AND 3',4',5-OXYGENATED PYRANOISOFLAVONES: ALPINUM ISOFLAVONE AND RELATED COMPOUNDS, AND REVISED STRUCTURE OF DERRONE

Alpinumisoflavone (4',5-dihydroxy-2",2"-dimethylpyranoisoflavone) (1a) was synthesized by regioselective reduction of 7-(4-hydroxyphenyl)-2,3-dihydro-5-methoxy-2,2-dimethyl-4H,6H-benzodipyran-4,6-dione (15a) with NaBH4 and dehydrati

SYNTHESIS OF ALPINUM ISOFLAVONE, DERRONE AND RELATED PYRANOISOFLAVONES

Reaction of phenacylchroman 1 with ethoxyalyl chloride in pyridine followed by hydrolysis of the resulting esters 2 and 3 and decarboxylation of the acids 4 and 5, gave dihydro-4'-O-methyl alpinum isoflavone 6 and 4'-O-methylderrone 7 respectively.Similarly 8 gave 11 which was selectively demethylated to 7.DDQ, dehydrogenation of 6, 7 and 11 gave 14, 15 and 17.Demethylation of 6 and 7 followed by dehydrogenation gave alpinum isoflavone 18 and derrone 19.