cas 357-07-3, OXYMORPHONE HCL NARCOTIC ANALGESIC

Articles about 357-07-3Total 8 be found

Processes for Making Opioids Including 14-Hydroxycodeinone and 14-hydroxymorphinone
Improved processes for making opioid products having low impurity levels including making 14-hydroxycodeinone and 14-hydroxymorphinone from thebaine and oripavine, respectively.
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(2016/03/14)

A method for synthesizing hydrochloric acid hydroxy morphinones
The invention discloses a synthesis method of oxymorphone hydrochloride. The synthesis method mainly comprises the following steps of: 1) alkalifying to obtain free alkali by taking oxycodone hydrochloride as an initial a raw material; 2) carrying out a demethylation reaction to obtain oxymorphone; 3) carrying out a hydrogenation reaction on the oxymorphone under acidic condition; and 4) salifying the hydrogenated product with hydrochloric acid to obtain the target product oxymorphone hydrochloride. The synthesis method disclosed by the invention has the advantages of available raw materials, high product purity and is easy to operate and is applicable to industrial production.
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(2017/02/17)

Forms of oxymorphone hydrochloride
The present disclosure is directed to crystalline forms of oxymorphone hydrochloride and compositions comprising any of the crystalline forms of oxymorphone hydrochloride. Also provided are processes for the preparation of crystalline forms of oxymorphone hydrochloride.
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Paragraph 0146

(2015/07/02)

PROCESS FOR IMPROVED OPIOID SYNTHESIS
Compounds and compositions for use as starting materials or intermediate materials in the preparation of opioids including, e.g., oxymorphone base and/or an oxymorphone salt; processes for preparing these compounds and compositions; uses of these compounds and compositions in the preparation of APIs and pharmaceutical dosage forms; and uses of said APIs and pharmaceutical dosage forms in the treatment of medical conditions.
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(2014/02/15)

IMPROVED METHOD OF PREPARING OXYMORPHONE
The invention relates to an improved method of preparing oxymorphone or a salt thereof from oripavine. In particular, the invention relates to a method of preparing oxymorphone with a content of alpha-beta- unsaturated ketones (ABUK) 10 ppm.
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Page/Page column 22

(2014/01/08)

CRYSTALLINE FORMS OF OXYMORPHONE HYDROCHLORIDE
The present invention is directed to crystalline forms of oxymorphone hydrochloride.
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Page/Page column 14-15

(2012/02/03)

PROCESS FOR PREPARING OXYMORPHONE
Methods are provided which include converting oripavine to other opiates, including converting oripavine to 14-hydroxymorphinone and/or converting 14-hydroxymorphinone to oxymorphone. Purification and salt formation are optionally included.
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Page/Page column 6; 9

(2008/12/05)

METHOD FOR MAKING ANALGESICS
Improved analgesic oxymorphone hydrochloride contains less than 10 ppm of alpha, beta unsaturated ketones and pharmaceutical preparations comprising such oxymorphone hydrochloride. The oxymorphone hydrochloride is produced by reducing a starting material oxymorphone hydrochloride using gaseous hydrogen and under specified acidity, solvent system and temperature conditions. A specific polymorph of oxymorphone hydrochloride may be obtained by hydration.
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Page/Page column 9; 10; 11

(2008/12/06)