3644-18-6

Basic information

• Product Name: 1-(2-DIMETHYLAMINOETHYL)PIPERAZINE
• Synonyms: 1-(2-DIMETHYLAMINOETHYL)PIPERAZINE;N,N-DIMETHYL-1-PIPERAZINEETHANAMINE;N,N-DIMETHYL-2-PIPERAZINOETHYLAMINE;RARECHEM AH CK 0089;TIMTEC-BB SBB010067;1-(2-Dimethylaminoethyl)piperazine 97%;1-Piperazineethanamine,N,N-dimethyl-(9CI);1-[2-(DIMETHYLAMINO)-ETHYL]-PIPERAZINE >98%
• CAS NO: 3644-18-6
• Molecular Formula: C₈H₁₉N₃
• Molecular Weight: 157.26
• Product Categories: PIPERIDINE
• Mol File: 3644-18-6.mol

Chemical Properties

• Boiling Point: 63 °C
• Flash Point: 78.8 °C
• Appearance: Clear yellow liquid
• Density: 0.918 g/cm³
• Vapor Pressure: 0.176mmHg at 25°C
• Refractive Index: n20/D 1.479
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.50±0.28(Predicted)
• BRN: 105841
• CAS DataBase Reference: 1-(2-DIMETHYLAMINOETHYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-DIMETHYLAMINOETHYL)PIPERAZINE(3644-18-6)
• EPA Substance Registry System: 1-(2-DIMETHYLAMINOETHYL)PIPERAZINE(3644-18-6)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2735 8/PG 3
• WGK Germany: 3
• F: 10-34
• HazardClass: IRRITANT
• Hazardous Substances Data: 3644-18-6(Hazardous Substances Data)

Usage

Chemical Properties

Clear yellow liquid

InChI:InChI=1/C8H19N3/c1-10(2)7-8-11-5-3-9-4-6-11/h9H,3-8H2,1-2H3/p+3

Upstream product

• 61308-25-6 Chloroethylpiperazine 
• 124-40-3 dimethyl amine 
• 103-76-4 1-(2-hydroxyethyl)piperazine 
• 614745-60-7 C₁₃H₂₇N₃O₂ 
• 77279-24-4 tert-butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate 
• 208167-83-3 tert-butyl 4-(2-chloroethyl)tetrahydro-1(2H)-pyrazinecarboxylate 
• 885699-05-8 4-(2-(dimethylamino)-2-oxoethyl)piperazine-1-carboxylic acid tert-butyl ester 
• 731810-20-1 tert-butyl 4-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate 

Downstream Products

• 444665-85-4 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-({4-[2-(dimethylamino)ethyl]piperazin-1-yl}sulfonyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one 
• 882048-00-2 4-(2-{4-[2-(dimethylamino)ethyl]piperazine-1-yl}-6-phenylpyrido[2,3-d]pyrimidin-7-yl)benzaldehyde 
• 912545-17-6 (2.4-bis-benzyloxy-5-isopropyl-phenyl)-[4-(2-dimethylamino-ethyl)-piperazin-1-yl]-methanone 
• 913483-58-6 {2-[4-(4-bromo-benzenesulfonyl)-piperazin-1-yl]-ethyl}-dimethyl-amine 
• 1260242-76-9 C₂₉H₃₄F₆N₈ 
• 1165798-99-1 tert-butyl [(trans-4-{[({2-[4-(2-(dimethylamino)ethyl)piperazin-1-yl]quinolin-4-yl}carbonyl)amino]methyl}cyclohexyl)methyl]carbamate 
• 1369390-18-0 [2-(4-(4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl)-piperazin-1-yl)-ethyl]-trimethyl-ammonium trifluoroacetate salt 

Relevant articles and documents

Natural product-based design, synthesis and biological evaluation of anthra[2,1-d]thiazole-6,11-dione derivatives from rhein as novel antitumour agents

Two series of novel 2-substituted 5,7-dihydroxyanthra[2,1-d]thiazole-6,11- dione derivatives from natural rhein were designed, synthesized and evaluated for their antitumour activities against human cancer cell lines A549 and HeLa in vitro.

Design and synthesis of novel sulfonamide-containing bradykinin hB 2 receptor antagonists. Synthesis and structure-relationships of α,α-tetrahydropyranylglycine

A series of α,α-cycloalkylglycine sulfonamide compounds of general formula 1 has previously been identified by our group as selective human B2(hB2) receptor antagonists. Here we report the in vitro and in vivo BK antagonist activity