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364635-60-9

(E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene

    Cas No: 364635-60-9

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  • (E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene

    Cas No: 364635-60-9

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  • 364635-60-9 Structure

  • Basic information

    1. Product Name: (E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene
    2. Synonyms: (E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene;(E/Z)-2,2-DiMethyl-propanoic Acid 4-[1-(4-hydroxyphenyl)-2-phenyl-1-butenyl]phenyl Ester
    3. CAS NO:364635-60-9
    4. Molecular Formula: C27H28O3
    5. Molecular Weight: 400.50942
    6. EINECS: N/A
    7. Product Categories: Aroamtics;Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals;Aroamtics, Drug Analogues, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 364635-60-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: Acetone, Dichloromethane, Methanol
    9. CAS DataBase Reference: (E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene(CAS DataBase Reference)
    10. NIST Chemistry Reference: (E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene(364635-60-9)
    11. EPA Substance Registry System: (E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene(364635-60-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 364635-60-9(Hazardous Substances Data)

364635-60-9 Usage

Chemical Properties

Off-White Solid

Check Digit Verification of cas no

The CAS Registry Mumber 364635-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,4,6,3 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 364635-60:
(8*3)+(7*6)+(6*4)+(5*6)+(4*3)+(3*5)+(2*6)+(1*0)=159
159 % 10 = 9
So 364635-60-9 is a valid CAS Registry Number.

364635-60-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (E/Z)-1-(4-Hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene

1.2 Other means of identification

Product number -
Other names 4-[(1E)-1-(4-Hydroxyphenyl)-2-phenyl-1-buten-1-yl]phenyl pivalate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:364635-60-9 SDS

364635-60-9Relevant articles and documents

NOVEL COMPOUNDS HAVING ESTROGEN RECEPTOR ALPHA DEGRADATION ACTIVITY AND USES THEREOF

-

, (2020/06/08)

The present disclosure relates to novel compounds having estrogen receptor alpha degradation activity, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.

ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS

-

, (2019/12/04)

The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

Synthesis and structure-activity relationships of ferrocenyl tamoxifen derivatives with modifed side chains

Nguyen, Anh,Top, Siden,Pigeon, Pascal,Vessieres, Anne,Hillard, Elizabeth A.,Plamont, Marie-Aude,Huche, Michel,Rigamonti, Clara,Jaouen, Gerard

scheme or table, p. 684 - 696 (2009/07/25)

We report here the synthesis and cell-proliferation properties of derivatives of the breast cancer drug tamoxifen, in which the -O(CH 2)2N-(CH3)2 side chain, responsible for the drug's antiestrogenic properties,

Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics

Rubin, Valeria N,Ruenitz, Peter C,Boudinot,Boyd, Jason L

, p. 1579 - 1587 (2007/10/03)

Previously, the estrogen receptor (ER) ligand 4-[1-(p-hydroxyphenyl)-2-phenylethyl]phenoxyacetic acid (5) was found to have differential bone loss suppressive effects in the ovariectomized (OVX) rat approaching those of selective ER modulators (SERMs) suc

Synthesis and Sulfatase Inhibitory Activities of (E)- and (Z)-4-Hydroxytamoxifen Sulfamates

Chu, Guo-Hua,Peters, Amy,Selcer, Kyle W.,Li, Pui-Kai

, p. 141 - 144 (2007/10/03)

We report the development of (E)- and (Z)-4-hydroxytamoxifen sulfamates as estrone sulfatase inhibitors, potential therapeutic agents for the treatment of breast cancer. Both compounds competitively inhibit estrone sulfatase isolated from rat liver with apparent Ki of 35.9 μM for (E)-4-hydroxytamoxifen sulfamate and an apparent Ki of >500 μM for the (Z) isomer.

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