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114031-67-3

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114031-67-3 Usage

Uses

4-Hydroxy-4’-(trimethylacetoxy)benzophenone (cas# 114031-67-3) is a compound useful in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 114031-67-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,0,3 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 114031-67:
(8*1)+(7*1)+(6*4)+(5*0)+(4*3)+(3*1)+(2*6)+(1*7)=73
73 % 10 = 3
So 114031-67-3 is a valid CAS Registry Number.

114031-67-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-(4-hydroxybenzoyl)phenyl] 2,2-dimethylpropanoate

1.2 Other means of identification

Product number -
Other names 4,4'-trimethylacetoxy hydroxy benzophenone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:114031-67-3 SDS

114031-67-3Relevant articles and documents

Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRγ

Chao, Esther Y.H.,Collins, Jon L.,Gaillard, Stephanie,Miller, Aaron B.,Wang, Liping,Orband-Miller, Lisa A.,Nolte, Robert T.,McDonnell, Donald P.,Willson, Timothy M.,Zuercher, William J.

, p. 821 - 824 (2006)

The design and synthesis of 4-hydroxytamoxifen (4-OHT) derivatives are described. The binding affinities of these compounds toward the orphan estrogen-related receptor γ and the classical estrogen receptor α demonstrate that analogs bearing hydroxyalkyl g

Rational design of ERα targeting hypoxia turn-on fluorescent probes with antiproliferative activity for breast cancer

Dong, Chune,Hu, Zhiye,Ma, Xiaoyu,Meng, Qiuyu,Xie, Baohua,Zhou, Fuling,Zhou, Hai-Bing

supporting information, p. 10493 - 10496 (2020/10/02)

The overexpression of estrogen receptor (ER) α is not only closely related to the development of ER+ breast cancer, but is also an important biomarker for clinical diagnosis and treatment. Herein, we report several ERα targeting hypoxia turn-on fluorescent probes with antitumor activity for breast cancer cells. Among them, probes 3 and 5 displayed good ERα targeting ability and favorable hypoxia turn-on response in MCF-7 cells. Moreover, the probes 3 and 5 exhibited good antiproliferative activity towards MCF-7 cells (IC50 = 8.5 μM, 10.3 μM) and a much lower cytotoxicity to normal cells compared with the positive control. It is expected that these novel fluorescent probes may provide useful tools for the theranostics of ER+ breast cancer.

ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS

-

Page/Page column 215, (2019/12/04)

The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

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