37463-94-8

Basic information

• Product Name: SULPHONYLDIACETONITRILE
• Synonyms: SULPHONYLDIACETONITRILE;SULFONYLDIACETONITRILE;2-[(CYANOMETHYL)SULFONYL]ACETONITRILE;2-[(cyanomethyl)sulphonyl]acetonitrile;Sulfonyldiacetonitrile,98%;2,2'-Sulfonylbisacetonitrile;Sulfonylbis(acetonitrile)
• CAS NO: 37463-94-8
• Molecular Formula: C₄H₄N₂O₂S
• Molecular Weight: 144.15
• Mol File: 37463-94-8.mol

Chemical Properties

• Melting Point: 141-142°C
• Boiling Point: 467.2°C at 760 mmHg
• Flash Point: 236.3°C
• Appearance: /
• Density: 1.408g/cm³
• Vapor Pressure: 6.67E-09mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: SULPHONYLDIACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: SULPHONYLDIACETONITRILE(37463-94-8)
• EPA Substance Registry System: SULPHONYLDIACETONITRILE(37463-94-8)

Safety Data

• Statements: 23/24/25
• Safety Statements: 22-36/37/39-45
• RIDADR: 3276
• Hazardous Substances Data: 37463-94-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Sulphonyldiacetonitrile is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, sulphonyldiacetonitrile is utilized as a building block for the production of agrochemicals, playing a vital role in the creation of effective pest control and crop protection solutions.
Used in Fine Chemicals Industry:
Sulphonyldiacetonitrile is employed as an essential component in the synthesis of fine chemicals, which are used in a wide range of applications, including fragrances, dyes, and specialty chemicals.
Used in Synthesis of Sulfonamides:
Sulphonyldiacetonitrile is used as an intermediate in the synthesis of sulfonamides, a class of antimicrobial agents that are widely used in the treatment of bacterial infections.
Used in Organic Synthesis:
Due to its strong electron-withdrawing properties, sulphonyldiacetonitrile is used as a reagent in the preparation of various organic compounds, particularly those containing nitrogen and sulfur atoms, enhancing the versatility and scope of organic synthesis.

InChI:InChI=1/C4H4N2O2S/c5-1-3-9(7,8)4-2-6/h3-4H2

Upstream product

• 37463-81-3 sulfonyl-bis-acetaldehyde dioxime 
• 112831-03-5 2,2'-Sulfonylbis<3-methoxy-(E,E)-2-propenenitrile> 

Downstream Products

• 77444-91-8 (2-Amino-1-cyclohexyl-4,5-dimethyl-1H-pyrrole-3-sulfonyl)-acetonitrile 
• 77444-92-9 2-amino-1-benzyl-3-cyanomethylsulfonyl-4,5-dimethylpyrrole 
• 112831-03-5 2,2'-Sulfonylbis<3-methoxy-(E,E)-2-propenenitrile> 
• 187804-96-2 2-amino-1-[2-(4-chlorophenyl)ethyl]-3-cyanomethylsulfonyl-4,5-dimethylpyrrole 
• 7014-08-6 2-phenylazo-2-phenylhydrazonoacetonitrile 
• 33556-21-7 1,5?bis(4?methoxyphenyl)?3?cyanoformazan 
• 7071-45-6 1,5-di(p-chlorophenyl)-3-cyanoformazane 
• 7071-14-9 1,5?bis(4?nitrophenyl)?3?cyanoformazan 
• 1384167-08-1 Pt(CH(CN)SO₂CH(CN))(1,2-bis(diphenylphosphino)ethane) 
• 1384167-09-2 trans-Pd(CH(CN)SO₂CH(CN))(triphenyphosphine)2 
• 1384167-09-2 cis-Pd(CH(CN)SO₂CH(CN))(triphenyphosphine)2 
• 1384167-10-5 trans-Pd(CH(CN)SO₂CH(CN))(1,2-bis(diphenylphosphino)ethane) 
• 1384167-10-5 cis-Pd(CH(CN)SO₂CH(CN))(1,2-bis(diphenylphosphino)ethane) 

Relevant articles and documents

Reagents for Bioorganic Synthesis. 4. A Novel Bifunctional Cross-Linking Reagent. Preparation, Structure, Properties, and Reactions of 2,2'-Sulfonylbis

The reagent 2,2'-sulfonylbis (1) was prepared by the reaction of 2,2'-sulfonyldiacetonitrile with excess trimethyl orthoformate, catalyzed by concentrated sulfuric acid.Configurational and conformational features of 1 wer