376-18-1

Basic information

• Product Name: 1H,1H,9H-Hexadecafluoro-1-nonanol
• Synonyms: 1,1,9-TRIHYDROPERFLUORONONANOL;2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-HEXADECAFLUORO-1-NONANOL;2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluorononan-1-ol;1H,1H,9H-HEXADECAFLUORO-1-NONANOL;1H,1H,9H-HEXADECAFLUORONONAN-1-OL;1H,1H,9H-HEXADECAFLUORONONANOL;1H,1H,9H-PERFLUORO-1-NONANOL;1H,1H,9H-PERFLUORONONAN-1-OL
• CAS NO: 376-18-1
• Molecular Formula: C₉H₄F₁₆O
• Molecular Weight: 432.1
• EINECS: 206-806-0
• Product Categories: Small molecule;organofluorine compounds
• Mol File: 376-18-1.mol

Chemical Properties

• Melting Point: 53-59 °C(lit.)
• Boiling Point: 155-156 °C200 mm Hg(lit.)
• Flash Point: 157-158°C/200mm
• Appearance: /
• Density: 1.6319 (estimate)
• Vapor Pressure: 0.0945mmHg at 25°C
• Refractive Index: 1.29
• PKA: 12.89±0.10(Predicted)
• BRN: 1808149
• CAS DataBase Reference: 1H,1H,9H-Hexadecafluoro-1-nonanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1H,1H,9H-Hexadecafluoro-1-nonanol(376-18-1)
• EPA Substance Registry System: 1H,1H,9H-Hexadecafluoro-1-nonanol(376-18-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39-44
• WGK Germany: 2
• RTECS: RA7905000
• TSCA: T
• HazardClass: IRRITANT
• Hazardous Substances Data: 376-18-1(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C9H4F16O/c10-2(11)4(14,15)6(18,19)8(22,23)9(24,25)7(20,21)5(16,17)3(12,13)1-26/h2,26H,1H2

Upstream product

• 67-56-1 methanol 
• 116-14-3 polytetrafluoroethylene 
• 302-17-0 chloral hydrate 

Downstream Products

• 307-99-3 1H,8H-perfluorooctane 
• 76-21-1 9H-hexadecafluorononanoic acid 
• 364379-59-9 p-2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-Hexadecafluorononoxy-m-nitrobenzoic acid 
• 17352-11-3 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluorononyl trifluoromethanesulfonate 
• 23588-89-8 triethylamine hydrofluoride 
• 678-45-5 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid 
• 140457-98-3 Benzenesulfonic acid 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluoro-nonyl ester 
• 129086-21-1 [2-(2-{2-[2-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-Hexadecafluoro-nonyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxymethyl]-benzene 
• 364379-56-6 p-2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-Hexadecafluorononoxy-m-nitrotrifluoromethylbenzene 
• 864-23-3 1H,1H,9H-Hexadecafluor-nonyl-p-tosylat 

Relevant articles and documents

Polyfluoroalloxy phosphonic and phosphinic acid derivatives: I. 1-Hydroxy-2,2,2-trichloroethylphosphinates

Polyfluoroalkyl esters of 1-hydroxy-2,2,2-trichloroethylphosphonic and aryl(alkyl-)phosphinic acids exhibited antienzyme activity towards esterases of animal and microbial origin. A good correlation is observed between high antiesterase activity of the target compounds and their physicochemical parameters, characterizing their structure.

Process for hydroxyalkylation of fluorinated alcohols

Mono O-hydroxyalkylated derivatives of 1,1-dihydroperfluorinated or 1H,1-alkylperfluorinated alcohols are prepared by reacting the alcohols with alkylene carbonates at a temperature of at least 60° C. in the presence of a one- or two-part catalyst. The catalyst is a nitrogenous base, optionally in combination with a tetraalkylammonium halide. The O-hydroxyalkylated derivatives are useful non-ionic surfactants and emulsifiable compounds for fire extinguishing systems.