382165-80-2Relevant articles and documents
Ionic liquid 1-(4-nitritobutyl)-3-methylimidazolium chloride as a new reagent for the efficient N-nitrosation of secondary amines under mild conditions
Valizadeh, Hassan,Gholipour, Hamid,Shomali, Ashkan
, p. 467 - 470 (2012)
1-(4-Nitritobutyl)-3-methylimidazolium chloride has been developed as a new reagent for efficient nitrosation of secondary amines at 0 °C to room temperature. A variety of N-nitrosamines were prepared in excellent yields by use of this task-specific ionic liquid under mild and heterogeneous conditions.
Chemoselective N-nitrosation of secondary amines under mild and heterogeneous conditions
Zolfigol,Choghamarani,Shirini,Keypour,Salehzadeh
, p. 359 - 365 (2001)
A combination of iodic or periodic acids and sodium nitrite in the presence of wet SiO2 was used as an effective nitrosating agent for the nitrosation of secondary amines to their corresponding nitroso derivatives under mild and heterogeneous conditions in excellent yields.
An efficient method for N-nitrosation of secondary amines under mild and, heterogeneous conditions
Zolfigol, Mohammad Ali,Ghaemi, Ezat,Madrakian, Elahe,Kiany-Borazjani, Maryam
, p. 2057 - 2060 (2000)
A combination of inorganic acidic salts or silica gel supported inorganic acids and sodium nitrite in the presence of wet SiO2 was used as an effective nitrosating agent for the nitrosation of secondary amines to their corresponding nitroso derivatives under mild and heterogeneous conditions in moderate to excellent yields. Mg(HSO4)2 and NaHSO4 are superior to all the aforementioned reagents in convenience, yield and purity of the isolated nitrosoamines.
Four-Coordinate Copper Halonitrosyl {CuNO}10 Complexes
Bower, Jamey K.,Sokolov, Alexander Yu.,Zhang, Shiyu
, p. 10225 - 10229 (2019)
While copper nitrosyl complexes are implicated in numerous biological systems, isolable examples remain limited. In this report, we show that [Cl3CuNO]?, with a {CuNO}10 electron configuration, can be generated by nitrite reduction at a copper(I) dichloride anion or by nitric oxide addition to a copper(II) trichloride precursor. The bromide analogue, [Br3CuNO]? was synthesized analogously, and both copper halonitrosyl complexes were characterized by X-ray diffraction and a variety of spectroscopic methods. Experimental data and multireference (CASSCF/NEVPT2) calculations provide strong evidence for a CuII–NO. ground state. Both [Cl3CuNO]? and [Br3CuNO]? release and recapture NO. reversibly, and exhibit nitrosative reactivities toward a wide range of biological nucleophiles, such as amines, alcohols, and thiols.
Effect of stirring devices on the intensification of gas-fluid processes
Ivanets,Al'brekht,Ivanets
, p. 461 - 465 (2001)
A comparative analysis is made of the operation of apparatus of rotary-pulsation and ejector types with self-suction turbine agitator. The dependence of the efficiency of operation on the output capacity and energy-related characteristics determining power consumption for agitation of gas-fluid mixtures were determined experimentally.
One-Pot Tandem ortho-Naphthoquinone-Catalyzed Aerobic Nitrosation of N-Alkylanilines and Rh(III)-Catalyzed C-H Functionalization Sequence to Indole and Aniline Derivatives
Si, Tengda,Kim, Hun Young,Oh, Kyungsoo
, p. 1152 - 1163 (2021/01/14)
The nitroso group served as a traceless directing group for the C-H functionalization of N-alkylanilines, ultimately removed after functioning either as an internal oxidant or under subsequent reducing conditions. The unique ability of o-NQ catalysts to aerobically oxidize the N-alkylanilines without using solvents and stoichiometric amounts of oxidants has rendered the new opportunity to develop the telescoped catalyst systems without a need for directly handling the hazardous N-nitroso compounds.
Access to Branched Allylarenes via Rhodium(III)-Catalyzed C-H Allylation of (Hetero)arenes with 2-Methylidenetrimethylene Carbonate
Zhang, Shang-Shi,Zheng, Yi-Chuan,Zhang, Zi-Wu,Chen, Shao-Yong,Xie, Hui,Shu, Bing,Song, Jia-Lin,Liu, Yan-Zhi,Zeng, Yao-Fu,Zhang, Luyong
supporting information, p. 5719 - 5723 (2021/08/16)
A rhodium(III)-catalyzed C-H allylation of (hetero)arenes by using 2-methylidenetrimethylene carbonate as an efficient allylic source has been developed for the first time. Five different directing groups including oxime, N-nitroso, purine, pyridine, and pyrimidine were compatible, delivering various branched allylarenes bearing an allylic hydroxyl group in moderate to excellent yields.
Rh(iii)-catalyzed, hydrazine-directed C-H functionalization with 1-alkynylcyclobutanols: A new strategy for 1: H -indazoles
Zhang, Lei,Chen, Junyu,Chen, Xiahe,Zheng, Xiangyun,Zhou, Jian,Zhong, Tianshuo,Chen, Zhiwei,Yang, Yun-Fang,Jiang, Xinpeng,She, Yuan-Bin,Yu, Chuanming
supporting information, p. 7415 - 7418 (2020/07/15)
Rh(iii)-catalyzed coupling of phenylhydrazines with 1-alkynylcyclobutanols was realized through a hydrazine-directed C-H functionalization pathway. This [4+1] annulation, based on the cleavage of a Csp-Csp triple bond in alkynylcyclobutanol, provides a new pathway to prepare diverse 1H-indazoles under mild reaction conditions. This journal is
4-amino diphenylamine preparation method
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Paragraph 0024-0065, (2019/04/06)
The invention discloses a 4-amino diphenylamine preparation method which includes the steps: slowly dropping concentrated hydrochloric acid into concentrated sulfuric acid, drying generated HCl gas bythe concentrated sulfuric acid and then leading the HCl gas into n-butyl alcohol for absorbing the gas; adding diphenylamine, sodium nitrite, water and methylbenzene, dissolving the diphenylamine bystirring, and then dropping hydrogen chloride for reaction with n-butyl alcohol solution; performing standing and liquid separation, removing water phase and organic phase vacuum desolvation agents, adding water, stirring the solution and performing suction filtration, washing and drying to obtain 4-nitroso diphenylamine; adding the 4-nitroso diphenylamine into an autoclave, adding solvents and catalysts, replacing air in the autoclave by hydrogen and performing hydrogenation reaction; filtering catalyzed hydrogenation liquid, decompressing the desolvation agents and finally performing rectification to obtain 4-amino diphenylamine. According to the preparation method, under the condition of low and medium pressure, composite skeleton nickel catalysts replace traditional noble metal catalysts for hydrogenation reduction of 4-amino diphenylamine, waste gas, waste water and industrial residues are fewer, environmental protection is benefited, and production cost is reduced.
Rhodium(iii)-catalyzed indole synthesis at room temperature using the transient oxidizing directing group strategy
Shang, Yaping,Jonnada, Krishna,Yedage, Subhash Laxman,Tu, Hua,Zhang, Xiaofeng,Lou, Xin,Huang, Shijun,Su, Weiping
supporting information, p. 9547 - 9550 (2019/08/15)
Rh-catalyzed reactions of N-alkyl anilines with internal alkynes at room temperature have been developed using an in situ generated N-nitroso group as a transient oxidizing directing group. Due to mild reaction conditions, this method enabled synthesis of a broad range of N-alkyl indoles, including even two indole-based medicinal compounds. Our work disclosed the feasibility of the transient oxidizing directing group strategy in C-H functionalization reactions, which possesses the potential to enhance overall step-economy and impart new reactivity patterns to substrates.
