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Benurestat, also known as p-Chlorohippurohydroxamic Acid, is a potent inhibitor of recombinant human glutathione transferase P1-1 and an enzyme inhibitor of urease. It is a small molecule with the ability to inhibit specific enzymes, making it a valuable compound in various applications.

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  • 38274-54-3 Structure
  • Basic information

    1. Product Name: benurestat
    2. Synonyms: benurestat;4-Chloro-N-(2-(hydroxyamino)-2-oxoethyl)benzamide
    3. CAS NO:38274-54-3
    4. Molecular Formula: C9H9ClN2O3
    5. Molecular Weight: 228.634
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 38274-54-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: 1.414g/cm3
    6. Refractive Index: 1.59
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: benurestat(CAS DataBase Reference)
    10. NIST Chemistry Reference: benurestat(38274-54-3)
    11. EPA Substance Registry System: benurestat(38274-54-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 38274-54-3(Hazardous Substances Data)

38274-54-3 Usage

Uses

Used in Pharmaceutical Industry:
Benurestat is used as an enzyme inhibitor for the inhibition of urease, an enzyme involved in the breakdown of urea in the body. This inhibition can be beneficial in treating conditions where urease activity is problematic, such as certain urinary tract infections and kidney stones.
Additionally, benurestat is used as a potent inhibitor of recombinant human glutathione transferase P1-1, a protein involved in the detoxification process in the body. Its inhibition can be useful in the development of drugs targeting this protein, potentially leading to novel therapeutic approaches for various diseases.
Used in Research Applications:
In the field of research, benurestat is used as a tool compound to study the function and role of urease and glutathione transferase P1-1 in various biological processes. By inhibiting these enzymes, researchers can gain insights into their mechanisms of action and their involvement in disease pathways, which can contribute to the development of new therapeutic strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 38274-54-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,2,7 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 38274-54:
(7*3)+(6*8)+(5*2)+(4*7)+(3*4)+(2*5)+(1*4)=133
133 % 10 = 3
So 38274-54-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H9ClN2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(13)12-15/h1-4,15H,5H2,(H,11,14)(H,12,13)

38274-54-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-N-[2-(hydroxyamino)-2-oxoethyl]benzamide

1.2 Other means of identification

Product number -
Other names EU-2826

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:38274-54-3 SDS

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